Kojic Acid

Kojic Acid

Tham số Thông số kỹ thuật
Tên sản phẩm Kojic Acid
Số CAS 501-30-4
Công thức phân tử C6H6O4
Trọng lượng phân tử 142.11 g/mol
Hình thức Bột tinh thể màu trắng đến trắng ngà
Phương pháp phân tích (HPLC) ≥99.0%
Điểm nóng chảy 152-155°C
Độ hòa tan Soluble in water, ethanol; slightly soluble in ether
Gói 25 kg fiber drum with double PE liner

Kojic Acid Structure

Từ đồng nghĩa: 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one, Kojic acid, 501-30-4, 5-Hydroxy-2-hydroxymethyl-4-pyrone, Kojic acid (natural), 2-Hydroxymethyl-5-hydroxy-γ-pyrone

Kojic acid is a natural pyrone derivative produced by the fermentation of carbohydrate sources with Aspergillus oryzae. Its structure features a γ-pyrone ring with a hydroxyl group at C-5 and a hydroxymethyl group at C-2, enabling chelation of metal ions and interaction with enzymatic active sites. This mechanism underlies its primary function as a tyrosinase inhibitor, relevant to skin brightening and anti-pigmentation.

Commercially available as a white to off-white crystalline powder, kojic acid is standardized to ≥99.0% purity (HPLC). It is widely used in cosmetic, pharmaceutical, and research applications. In personal care, it is incorporated into serums, creams, and lotions targeting hyperpigmentation and uneven skin tone. In pharmaceuticals, it serves as a precursor for various synthetic intermediates.

Cấu trúc và tính chất hóa học

Kojic acid (C6H6O4) has a molecular weight of 142.11 g/mol and a melting point of 152-155°C. It is soluble in water and ethanol, slightly soluble in ether, and exhibits strong UV absorption. The compound is stable under normal storage conditions but may chelate with metal ions, affecting formulation stability.

Cơ chế tác dụng

  • Tyrosinase inhibition: Kojic acid chelates copper ions at the active site of tyrosinase, reversibly inhibiting the enzyme’s catalytic activity.
  • Antioxidant activity: Scavenges free radicals and reduces oxidative stress in skin cells.
  • Melanin synthesis suppression: Interferes with the polymerization of melanin precursors, leading to reduced pigmentation.
  • Antimicrobial effects: Exhibits bacteriostatic and fungistatic properties against certain strains.

Quality Specifications (QC Tests)

Test Item Thông số kỹ thuật
Xác định IR spectrum conforms to reference standard
Mất mát khi sấy khô ≤0.5%
Hàm lượng tro sau khi đốt ≤0.1%
Kim loại nặng ≤10 ppm
Giới hạn vi sinh vật Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g
Các chất liên quan Total impurities ≤1.0%

Cung ứng và Tài liệu

  • Công suất: 20 metric tons per month
  • Thời gian thực hiện: 3-5 business days (stock items)
  • Tài liệu hướng dẫn: COA, MSDS, TDS sẽ được cung cấp theo yêu cầu
  • Bao bì: 25 kg fiber drum with double PE liner, or as per customer requirement

Các câu hỏi thường gặp

What is the MOQ for Kojic Acid?

Our standard MOQ is 25 kg. For trial orders, we can accommodate smaller quantities; please contact us for details.

What is the delivery time?

For stock items, delivery is 3-5 business days after order confirmation.

Can you provide a COA and samples?

Yes, we provide a COA for each batch. Samples are available upon request; please contact our sales team for arrangements.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

send us your specification for a quotation.

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Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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