| Product Name | Trigonelline |
| CAS Number | 535-83-1 |
| Molecular Formula | C₇H₇NO₂ |
| Molecular Weight | 137.14 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Storage | Cool, dry, sealed |
| Shelf Life | 24 months |
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Trigonelline is a naturally occurring alkaloid found in coffee beans, fenugreek seeds (Trigonella foenum-graecum, from which its name derives), and other plants. It is the N-methyl betaine of nicotinic acid (niacin) and serves as a key biomarker for coffee authenticity and quality.
Primary applications: Analytical reference standard, coffee quality marker, and research compound.
Trigonelline Derived from Coffee
Synonyms:
Betain nicotinate
Caffearine / Coffearin / Coffearine
Gynesine
Nicotinic acid N-methylbetaine
N-Methylnicotinic acid betaine
| Parameter | Specification | Test Method |
|---|---|---|
| Assay (HPLC) | ≥ 98.0% | HPLC-UV |
| Appearance | White to off-white crystalline powder | Visual |
| Identification | HPLC retention time, NMR | HPLC/NMR |
| Loss on Drying | ≤ 0.5% | USP <731> |
| Residue on Ignition | ≤ 0.1% | USP <281> |
| Heavy Metals | ≤ 10 ppm | ICP-MS |
| Related Substances | Single impurity ≤ 0.5%; Total ≤ 2.0% | HPLC-UV |
| Residual Solvents | Meet USP <467> | GC |
| Application | Description | End Users |
|---|---|---|
| Coffee authenticity marker | Determines coffee type (arabica vs. robusta) and quality | Coffee industry QC labs |
| Analytical reference standard | Quantification of trigonelline in food and botanical samples | Analytical labs, food QC |
| Fenugreek extract standardization | Marker compound for fenugreek supplement quality | Nutraceutical QC |
| Metabolic research | Studying nicotinic acid metabolism | Pharmaceutical R&D |
| Traditional medicine research | Bioactivity studies of fenugreek and coffee | Herbal research |
Purity: ≥98.0% (HPLC)
Source: Plant-derived (semi-synthetic / natural extraction)
Monthly capacity: 10+ kg
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS, TDS, HPLC chromatogram, NMR (upon request)
Packaging: 10g – 1kg
📧 Email: info@lyvbio.com
Q: What is the difference between Trigonelline and Nicotinic acid (Niacin)?
A: Trigonelline is the N-methyl betaine of nicotinic acid. It is a methylated derivative, not vitamin B3 itself.
Q: Why is Trigonelline used as a coffee quality marker?
A: Trigonelline content differs significantly between Coffea arabica (higher) and Coffea robusta (lower). It is a key indicator for coffee authenticity and grade.
Q: Is Trigonelline water-soluble?
A: Yes. Trigonelline is freely soluble in water.
Q: What is your MOQ?
A: Research samples: 10g–100g. Bulk: 500g–1kg.
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