Salidroside

Salidroside

Tên sản phẩm Salidroside
Số CAS 10338-51-9
Các tên gọi khác Rhodioloside, Tyrosol glucoside
Công thức phân tử C14H20O7
Trọng lượng phân tử 300.30 g/mol
Hình thức Bột tinh thể màu trắng đến trắng ngà
Phương pháp phân tích (HPLC) ≥98,01 TP3T
Độ hòa tan Soluble in water, ethanol, and methanol
Mất mát khi sấy khô ≤2.0%
Hàm lượng tro sau khi đốt ≤0.5%
Kim loại nặng ≤10 ppm
Gói 25 kg net weight in fiber drums with double polyethylene liners

Salidroside Structure

Từ đồng nghĩa: Rhodioloside, Tyrosol glucoside, Salidroside, (4-Hydroxyphenyl)methyl β-D-glucopyranoside, 4-Hydroxyphenethyl β-D-glucopyranoside, Rhodiola rosea extract

Salidroside is a phenylpropanoid glycoside and the primary bioactive marker in Rhodiola rosea, a high-altitude perennial plant long valued in traditional medicine across Scandinavia, Siberia, and the mountainous regions of Asia. For centuries, Rhodiola rosea—often called golden root or Arctic root—has been used to combat fatigue, enhance physical endurance, and support mental clarity under stressful conditions. Salidroside, along with its aglycone tyrosol, represents the chemical foundation of these traditional applications and has become a focal point for modern research into adaptogenic and neuroprotective compounds.

Structurally, salidroside consists of a tyrosol moiety (4-hydroxyphenethyl alcohol) linked to a glucose unit via a β-glycosidic bond. This glycosylation enhances its water solubility and influences its pharmacokinetic profile compared to the aglycone. In the plant, salidroside accumulates in the rhizomes and roots, often in concentrations ranging from 0.5% to 2% in dried material, depending on species, harvest time, and growing conditions. Its presence is frequently used to standardize Rhodiola extracts, ensuring consistent biological activity across batches.

Beyond its role as a marker compound, salidroside has attracted significant attention in the nutraceutical, pharmaceutical, and cosmetic industries. It is incorporated into dietary supplements aimed at stress management and cognitive performance, as well as into skincare formulations targeting oxidative stress and inflammation. The compound is also a subject of ongoing clinical and preclinical studies exploring its mechanisms in cellular energy metabolism, neuroprotection, and cardiovascular health.

Chức năng

  • Adaptogenic activity: Helps the body resist physical and mental stress by modulating the hypothalamic-pituitary-adrenal axis.
  • Neuroprotective effects: Supports neuronal survival and cognitive function through antioxidant and anti-apoptotic pathways.
  • Antioxidant activity: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
  • Cardiovascular support: May improve endothelial function and protect against ischemia-reperfusion injury.
  • Anti-fatigue: Enhances physical endurance and reduces recovery time in exercise models.
  • Chống viêm: Inhibits pro-inflammatory cytokines and mediators.

Nguồn gốc và tiêu chuẩn hóa

  • Nguồn: Roots and rhizomes of Rhodiola rosea L.
  • Extraction: Aqueous or hydroalcoholic extraction, followed by purification and crystallization.
  • Tiêu chuẩn hóa: ≥98.0% salidroside (HPLC).
  • Forms: White to off-white crystalline powder.
  • Ứng dụng: Dietary supplements, functional foods, pharmaceuticals, cosmetic formulations, research.

Thông số kỹ thuật

Tham số Thông số kỹ thuật
Phương pháp phân tích (HPLC) ≥98,01 TP3T
Xác định NMR, MS conforms to structure
Mất mát khi sấy khô ≤2.0%
Hàm lượng tro sau khi đốt ≤0.5%
Kim loại nặng ≤10 ppm
Giới hạn vi sinh vật Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent

Documentation & Supply

  • Công suất hàng tháng: 500 kg
  • Thời gian thực hiện: 3-5 business days (stock items)
  • Tài liệu hướng dẫn: COA, MSDS, TDS, and additional regulatory support available upon request
  • Bao bì: 25 kg fiber drums with double polyethylene liners, or customized packaging for small quantities

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