Salidroside

Synonyme: Rhodioloside, Tyrosol glucoside, Salidroside, (4-Hydroxyphenyl)methyl β-D-glucopyranoside, 4-Hydroxyphenethyl β-D-glucopyranoside, Rhodiola rosea extract

Salidroside is a phenylpropanoid glycoside and the primary bioactive marker in Rhodiola rosea, a high-altitude perennial plant long valued in traditional medicine across Scandinavia, Siberia, and the mountainous regions of Asia. For centuries, Rhodiola rosea—often called golden root or Arctic root—has been used to combat fatigue, enhance physical endurance, and support mental clarity under stressful conditions. Salidroside, along with its aglycone tyrosol, represents the chemical foundation of these traditional applications and has become a focal point for modern research into adaptogenic and neuroprotective compounds.

Structurally, salidroside consists of a tyrosol moiety (4-hydroxyphenethyl alcohol) linked to a glucose unit via a β-glycosidic bond. This glycosylation enhances its water solubility and influences its pharmacokinetic profile compared to the aglycone. In the plant, salidroside accumulates in the rhizomes and roots, often in concentrations ranging from 0.5% to 2% in dried material, depending on species, harvest time, and growing conditions. Its presence is frequently used to standardize Rhodiola extracts, ensuring consistent biological activity across batches.

Beyond its role as a marker compound, salidroside has attracted significant attention in the nutraceutical, pharmaceutical, and cosmetic industries. It is incorporated into dietary supplements aimed at stress management and cognitive performance, as well as into skincare formulations targeting oxidative stress and inflammation. The compound is also a subject of ongoing clinical and preclinical studies exploring its mechanisms in cellular energy metabolism, neuroprotection, and cardiovascular health.

Funktion

• Adaptogenic activity: Helps the body resist physical and mental stress by modulating the hypothalamic-pituitary-adrenal axis.
• Neuroprotective effects: Supports neuronal survival and cognitive function through antioxidant and anti-apoptotic pathways.
• Antioxidant activity: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
• Cardiovascular support: May improve endothelial function and protect against ischemia-reperfusion injury.
• Anti-fatigue: Enhances physical endurance and reduces recovery time in exercise models.
• Anti-inflammatory: Inhibits pro-inflammatory cytokines and mediators.

Source & Standardization

• Quelle: Roots and rhizomes of Rhodiola rosea L.
• Extraction: Aqueous or hydroalcoholic extraction, followed by purification and crystallization.
• Standardization: ≥98.0% salidroside (HPLC).
• Forms: White to off-white crystalline powder.
• Anwendungen: Dietary supplements, functional foods, pharmaceuticals, cosmetic formulations, research.

Technische Daten

Documentation & Supply

• Monthly capacity: 500 kg
• Lieferzeit: 3–5 Werktage (Lagerware)
• Dokumentation: COA, MSDS, TDS, and additional regulatory support available upon request
• Verpackung: 25 kg fiber drums with double polyethylene liners, or customized packaging for small quantities

Angebotsanfrage

• LyvBio GmbH. — E-Mail: info@lyvbio.com