Salidroside

Salidroside

製品名 Salidroside
CAS番号 10338-51-9
別名 Rhodioloside, Tyrosol glucoside
分子式 C14H20O7
分子量 300.30 g/mol
外観 白色からオフホワイトの結晶性粉末
分析(HPLC) ≥98.0%
溶解度 Soluble in water, ethanol, and methanol
乾燥減量 ≤2.0%
焼失残渣 ≤0.5%
重金属 10 ppm以下
パッケージ 25 kg net weight in fiber drums with double polyethylene liners

Salidroside Structure

同義語: Rhodioloside, Tyrosol glucoside, Salidroside, (4-Hydroxyphenyl)methyl β-D-glucopyranoside, 4-Hydroxyphenethyl β-D-glucopyranoside, Rhodiola rosea extract

Salidroside is a phenylpropanoid glycoside and the primary bioactive marker in Rhodiola rosea, a high-altitude perennial plant long valued in traditional medicine across Scandinavia, Siberia, and the mountainous regions of Asia. For centuries, Rhodiola rosea—often called golden root or Arctic root—has been used to combat fatigue, enhance physical endurance, and support mental clarity under stressful conditions. Salidroside, along with its aglycone tyrosol, represents the chemical foundation of these traditional applications and has become a focal point for modern research into adaptogenic and neuroprotective compounds.

Structurally, salidroside consists of a tyrosol moiety (4-hydroxyphenethyl alcohol) linked to a glucose unit via a β-glycosidic bond. This glycosylation enhances its water solubility and influences its pharmacokinetic profile compared to the aglycone. In the plant, salidroside accumulates in the rhizomes and roots, often in concentrations ranging from 0.5% to 2% in dried material, depending on species, harvest time, and growing conditions. Its presence is frequently used to standardize Rhodiola extracts, ensuring consistent biological activity across batches.

Beyond its role as a marker compound, salidroside has attracted significant attention in the nutraceutical, pharmaceutical, and cosmetic industries. It is incorporated into dietary supplements aimed at stress management and cognitive performance, as well as into skincare formulations targeting oxidative stress and inflammation. The compound is also a subject of ongoing clinical and preclinical studies exploring its mechanisms in cellular energy metabolism, neuroprotection, and cardiovascular health.

機能

  • Adaptogenic activity: Helps the body resist physical and mental stress by modulating the hypothalamic-pituitary-adrenal axis.
  • Neuroprotective effects: Supports neuronal survival and cognitive function through antioxidant and anti-apoptotic pathways.
  • Antioxidant activity: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
  • Cardiovascular support: May improve endothelial function and protect against ischemia-reperfusion injury.
  • Anti-fatigue: Enhances physical endurance and reduces recovery time in exercise models.
  • 抗炎症作用: Inhibits pro-inflammatory cytokines and mediators.

Source & Standardization

  • 出典: Roots and rhizomes of Rhodiola rosea L.
  • Extraction: Aqueous or hydroalcoholic extraction, followed by purification and crystallization.
  • Standardization: ≥98.0% salidroside (HPLC).
  • Forms: White to off-white crystalline powder.
  • 用途: Dietary supplements, functional foods, pharmaceuticals, cosmetic formulations, research.

仕様

パラメータ 仕様
分析(HPLC) ≥98.0%
識別 NMR, MS conforms to structure
乾燥減量 ≤2.0%
焼失残渣 ≤0.5%
重金属 10 ppm以下
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent

資料・供給

  • 月間処理能力: 500 kg
  • リードタイム: 3~5営業日(在庫品)
  • ドキュメント: COA, MSDS, TDS, and additional regulatory support available upon request
  • パッケージ: 25 kg fiber drums with double polyethylene liners, or customized packaging for small quantities

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