N-Acetyl-L-cysteine Ethyl Ester (NACET)
| Tên sản phẩm | N-Acetyl-L-cysteine Ethyl Ester (NACET) |
|---|---|
| Số CAS | 59587-09-6 |
| Synonyms | NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate |
| Công thức phân tử | C7H13NO3S |
| Trọng lượng phân tử | 191.25 g/mol |
| Hình thức | Bột tinh thể màu trắng đến trắng ngà |
| Phương pháp phân tích (HPLC) | ≥98,01 TP3T |
| Mất mát khi sấy khô | ≤0.5% |
| Hàm lượng tro sau khi đốt | ≤0.1% |
| Kim loại nặng | ≤10 ppm |
| Độ hòa tan | Soluble in water, ethanol, and dimethyl sulfoxide |
| Lưu trữ | Store in a cool, dry place, protected from light and moisture |
| Gói | 25 kg net weight in fiber drums with double polyethylene liners |
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Từ đồng nghĩa: NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate
N-Acetyl-L-cysteine Ethyl Ester (NACET) is a lipophilic derivative of N-acetyl-L-cysteine (NAC), designed to improve cellular uptake and bioavailability. Unlike its parent compound, NACET carries an ethyl ester moiety that masks the carboxyl group, allowing it to passively diffuse across cell membranes and rapidly hydrolyze intracellularly to release free NAC. This prodrug strategy has made NACET a subject of growing interest in pharmaceutical and nutraceutical research, particularly for applications where NAC’s poor membrane permeability and low oral bioavailability limit its efficacy.
As a synthetic small molecule, NACET is manufactured under strict quality control to ensure high purity and consistent performance. It is primarily used as an active pharmaceutical ingredient (API) in investigational drugs, as a research chemical in oxidative stress and glutathione modulation studies, and as a premium ingredient in advanced dietary supplements targeting antioxidant support and detoxification.
| Tham số | Thông số kỹ thuật |
|---|---|
| Hình thức | Bột tinh thể màu trắng đến trắng ngà |
| Phương pháp phân tích (HPLC) | ≥98,01 TP3T |
| Mất mát khi sấy khô | ≤0.5% |
| Hàm lượng tro sau khi đốt | ≤0.1% |
| Kim loại nặng | ≤10 ppm |
| Độ hòa tan | Soluble in water, ethanol, and DMSO |
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