N-アセチル-L-システインエチルエステル(NACET)

N-アセチル-L-システインエチルエステル(NACET)

製品名 N-アセチル-L-システインエチルエステル(NACET)
CAS番号 59587-09-6
同義語 NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate
分子式 C7H13NO3S
分子量 191.25 g/mol
外観 白色からオフホワイトの結晶性粉末
分析(HPLC) ≥98.0%
乾燥減量 ≤0.5%
焼失残渣 ≤0.11 TP3T
重金属 10 ppm以下
溶解度 Soluble in water, ethanol, and dimethyl sulfoxide
ストレージ Store in a cool, dry place, protected from light and moisture
パッケージ 25 kg net weight in fiber drums with double polyethylene liners

N-Acetyl-L-cysteine Ethyl Ester (NACET) Structure

同義語: NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate

N-Acetyl-L-cysteine Ethyl Ester (NACET) is a lipophilic derivative of N-acetyl-L-cysteine (NAC), designed to improve cellular uptake and bioavailability. Unlike its parent compound, NACET carries an ethyl ester moiety that masks the carboxyl group, allowing it to passively diffuse across cell membranes and rapidly hydrolyze intracellularly to release free NAC. This prodrug strategy has made NACET a subject of growing interest in pharmaceutical and nutraceutical research, particularly for applications where NAC’s poor membrane permeability and low oral bioavailability limit its efficacy.

As a synthetic small molecule, NACET is manufactured under strict quality control to ensure high purity and consistent performance. It is primarily used as an active pharmaceutical ingredient (API) in investigational drugs, as a research chemical in oxidative stress and glutathione modulation studies, and as a premium ingredient in advanced dietary supplements targeting antioxidant support and detoxification.

製品の特長

  • 高純度: ≥98% by HPLC, meeting rigorous industry standards.
  • Enhanced Bioavailability: Ethyl ester form facilitates rapid cellular uptake and efficient conversion to NAC.
  • Versatile Applications: Suitable for pharmaceuticals, nutraceuticals, and research.
  • Regulatory Support: Available with comprehensive documentation including COA, MSDS, and TDS.
  • Scalable Supply: Consistent commercial quantities with flexible packaging options.
  • Quality Assurance: Manufactured in ISO-certified facilities with full traceability.

用途

  • Investigational pharmaceutical formulations for antioxidant therapy.
  • Dietary supplements aimed at boosting glutathione levels.
  • Research on oxidative stress, inflammation, and detoxification.
  • Cosmetic formulations for skin protection and anti-aging.
  • Cell culture studies requiring intracellular cysteine delivery.

仕様

パラメータ 仕様
外観 白色からオフホワイトの結晶性粉末
分析(HPLC) ≥98.0%
乾燥減量 ≤0.5%
焼失残渣 ≤0.11 TP3T
重金属 10 ppm以下
溶解度 Soluble in water, ethanol, and DMSO

発注・調達

  • パッケージ: 25 kg fiber drums with double polyethylene liners; custom packaging available upon request.
  • 最小注文数量(MOQ): 1 kg for trial orders; 25 kg for commercial orders.
  • リードタイム: 3~5営業日(在庫品)
  • ドキュメント: COA, MSDS, TDS, and other regulatory documents provided upon request.

見積依頼

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