N-Acetyl-L-cysteine Ethyl Ester (NACET)

N-Acetyl-L-cysteine Ethyl Ester (NACET)

Название продукта N-Acetyl-L-cysteine Ethyl Ester (NACET)
Номер CAS 59587-09-6
Синонимы NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate
Молекулярная формула C7H13NO3S
Молекулярная масса 191.25 g/mol
Внешний вид Кристаллический порошок от белого до небелого цвета
Анализ (ВЭЖХ) ≥98.0%
Потери при сушке ≤0,51 TP3T
Остаток после прокаливания ≤0,11 TP3T
Тяжелые металлы ≤10 ppm
Растворимость Soluble in water, ethanol, and dimethyl sulfoxide
Хранение Store in a cool, dry place, protected from light and moisture
Упаковка 25 kg net weight in fiber drums with double polyethylene liners

N-Acetyl-L-cysteine Ethyl Ester (NACET) Structure

Синонимы: NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate

N-Acetyl-L-cysteine Ethyl Ester (NACET) is a lipophilic derivative of N-acetyl-L-cysteine (NAC), designed to improve cellular uptake and bioavailability. Unlike its parent compound, NACET carries an ethyl ester moiety that masks the carboxyl group, allowing it to passively diffuse across cell membranes and rapidly hydrolyze intracellularly to release free NAC. This prodrug strategy has made NACET a subject of growing interest in pharmaceutical and nutraceutical research, particularly for applications where NAC’s poor membrane permeability and low oral bioavailability limit its efficacy.

As a synthetic small molecule, NACET is manufactured under strict quality control to ensure high purity and consistent performance. It is primarily used as an active pharmaceutical ingredient (API) in investigational drugs, as a research chemical in oxidative stress and glutathione modulation studies, and as a premium ingredient in advanced dietary supplements targeting antioxidant support and detoxification.

Основные особенности продукта

  • Высокая степень чистоты: ≥98% by HPLC, meeting rigorous industry standards.
  • Enhanced Bioavailability: Ethyl ester form facilitates rapid cellular uptake and efficient conversion to NAC.
  • Versatile Applications: Suitable for pharmaceuticals, nutraceuticals, and research.
  • Regulatory Support: Available with comprehensive documentation including COA, MSDS, and TDS.
  • Scalable Supply: Consistent commercial quantities with flexible packaging options.
  • Quality Assurance: Manufactured in ISO-certified facilities with full traceability.

Приложения

  • Investigational pharmaceutical formulations for antioxidant therapy.
  • Dietary supplements aimed at boosting glutathione levels.
  • Research on oxidative stress, inflammation, and detoxification.
  • Cosmetic formulations for skin protection and anti-aging.
  • Cell culture studies requiring intracellular cysteine delivery.

Технические характеристики

Параметр Технические характеристики
Внешний вид Кристаллический порошок от белого до небелого цвета
Анализ (ВЭЖХ) ≥98.0%
Потери при сушке ≤0,51 TP3T
Остаток после прокаливания ≤0,11 TP3T
Тяжелые металлы ≤10 ppm
Растворимость Soluble in water, ethanol, and DMSO

Заказы и поставки

  • Packaging: 25 kg fiber drums with double polyethylene liners; custom packaging available upon request.
  • MOQ: 1 kg for trial orders; 25 kg for commercial orders.
  • Срок выполнения заказа: 3–5 рабочих дней (товары, имеющиеся в наличии)
  • Documentation: COA, MSDS, TDS, and other regulatory documents provided upon request.

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