N-Acetyl-L-cysteine Ethyl Ester (NACET)
| Название продукта | N-Acetyl-L-cysteine Ethyl Ester (NACET) |
|---|---|
| Номер CAS | 59587-09-6 |
| Синонимы | NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate |
| Молекулярная формула | C7H13NO3S |
| Молекулярная масса | 191.25 g/mol |
| Внешний вид | Кристаллический порошок от белого до небелого цвета |
| Анализ (ВЭЖХ) | ≥98.0% |
| Потери при сушке | ≤0,51 TP3T |
| Остаток после прокаливания | ≤0,11 TP3T |
| Тяжелые металлы | ≤10 ppm |
| Растворимость | Soluble in water, ethanol, and dimethyl sulfoxide |
| Хранение | Store in a cool, dry place, protected from light and moisture |
| Упаковка | 25 kg net weight in fiber drums with double polyethylene liners |
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Синонимы: NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate
N-Acetyl-L-cysteine Ethyl Ester (NACET) is a lipophilic derivative of N-acetyl-L-cysteine (NAC), designed to improve cellular uptake and bioavailability. Unlike its parent compound, NACET carries an ethyl ester moiety that masks the carboxyl group, allowing it to passively diffuse across cell membranes and rapidly hydrolyze intracellularly to release free NAC. This prodrug strategy has made NACET a subject of growing interest in pharmaceutical and nutraceutical research, particularly for applications where NAC’s poor membrane permeability and low oral bioavailability limit its efficacy.
As a synthetic small molecule, NACET is manufactured under strict quality control to ensure high purity and consistent performance. It is primarily used as an active pharmaceutical ingredient (API) in investigational drugs, as a research chemical in oxidative stress and glutathione modulation studies, and as a premium ingredient in advanced dietary supplements targeting antioxidant support and detoxification.
| Параметр | Технические характеристики |
|---|---|
| Внешний вид | Кристаллический порошок от белого до небелого цвета |
| Анализ (ВЭЖХ) | ≥98.0% |
| Потери при сушке | ≤0,51 TP3T |
| Остаток после прокаливания | ≤0,11 TP3T |
| Тяжелые металлы | ≤10 ppm |
| Растворимость | Soluble in water, ethanol, and DMSO |
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