N-Acetyl-L-cysteine Ethyl Ester (NACET)

Synonyms: NACET, N-Acetyl-L-cysteine ethyl ester, Ethyl N-acetyl-L-cysteinate, (R)-Ethyl 2-acetamido-3-mercaptopropanoate

N-Acetyl-L-cysteine Ethyl Ester (NACET) is a lipophilic derivative of N-acetyl-L-cysteine (NAC), designed to improve cellular uptake and bioavailability. Unlike its parent compound, NACET carries an ethyl ester moiety that masks the carboxyl group, allowing it to passively diffuse across cell membranes and rapidly hydrolyze intracellularly to release free NAC. This prodrug strategy has made NACET a subject of growing interest in pharmaceutical and nutraceutical research, particularly for applications where NAC’s poor membrane permeability and low oral bioavailability limit its efficacy.

As a synthetic small molecule, NACET is manufactured under strict quality control to ensure high purity and consistent performance. It is primarily used as an active pharmaceutical ingredient (API) in investigational drugs, as a research chemical in oxidative stress and glutathione modulation studies, and as a premium ingredient in advanced dietary supplements targeting antioxidant support and detoxification.

Product Highlights

• High Purity: ≥98% by HPLC, meeting rigorous industry standards.
• Enhanced Bioavailability: Ethyl ester form facilitates rapid cellular uptake and efficient conversion to NAC.
• Versatile Applications: Suitable for pharmaceuticals, nutraceuticals, and research.
• Regulatory Support: Available with comprehensive documentation including COA, MSDS, and TDS.
• Scalable Supply: Consistent commercial quantities with flexible packaging options.
• Quality Assurance: Manufactured in ISO-certified facilities with full traceability.

Applications

• Investigational pharmaceutical formulations for antioxidant therapy.
• Dietary supplements aimed at boosting glutathione levels.
• Research on oxidative stress, inflammation, and detoxification.
• Cosmetic formulations for skin protection and anti-aging.
• Cell culture studies requiring intracellular cysteine delivery.

Specifications

Ordering & Supply

• Packaging: 25 kg fiber drums with double polyethylene liners; custom packaging available upon request.
• MOQ: 1 kg for trial orders; 25 kg for commercial orders.
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS, and other regulatory documents provided upon request.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com