| Название продукта | Ergothioneine |
|---|---|
| Номер CAS | 497-30-3 |
| Молекулярная формула | C₉H₁₅N₃O₂S |
| Молекулярная масса | 229.30 g/mol |
| Внешний вид | Кристаллический порошок от белого до небелого цвета |
| Анализ (ВЭЖХ) | ≥ 98.0% – 99.5% (per grade) |
| Потери при сушке | ≤ 0,51 TP3T |
| Остаток после прокаливания | ≤ 0,11 TP3T |
| Тяжелые металлы | ≤ 10 ppm |
| Температура плавления | 260 – 270°C (decomposes) |
| Удельное вращение | +120° to +130° |
| Хранение | Хранить в прохладном, сухом месте, защищая от света |
| Растворимость | Soluble in water, DMSO; slightly soluble in ethanol |
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Синонимы: Ergothioneine, L-Ergothioneine, Ergothioneine (EGT), (S)-α-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium inner salt, Thiohistidine betaine, 2-Mercaptohistidine trimethylbetaine, EGT, L-(+)-Ergothioneine
Ergothioneine (EGT) is a naturally occurring amino acid derivative and a potent antioxidant with unique properties. It is synthesized by certain fungi, actinomycetes, and cyanobacteria, and is accumulated in the human body through dietary sources, particularly mushrooms (especially shiitake and oyster mushrooms), black beans, and organ meats. Humans cannot synthesize ergothioneine endogenously, making it a conditionally essential nutrient.
Ergothioneine is distinguished from other antioxidants by its specific transporter, OCTN1 (SLC22A4) , which actively transports EGT into cells, enabling its accumulation at high concentrations in tissues exposed to high oxidative stress, including the liver, kidney, red blood cells, and the lens and retina of the eye. This targeted accumulation, combined with its powerful free radical scavenging activity and its ability to chelate metal ions, provides robust protection against cellular oxidative damage.
Ergothioneine is widely used in dietary supplements, functional foods, cosmetic formulations, and research applications targeting healthy aging, neurological health, skin protection, and cardiovascular support.
Источник: Fermentation (using Lentinula edodes, Agaricus bisporus, or recombinant microorganisms) or synthetic production
Стандартизация: ≥98.0% – 99.5% ergothioneine (HPLC)
Формы: Белый или почти белый кристаллический порошок
Приложения: Dietary supplements, functional foods, cosmetics, research reagents