| 製品名 | Ergothioneine |
|---|---|
| CAS番号 | 497-30-3 |
| 分子式 | C₉H₁₅N₃O₂S |
| 分子量 | 229.30 g/mol |
| 外観 | 白色からオフホワイトの結晶性粉末 |
| 分析(HPLC) | ≥ 98.0% – 99.5% (per grade) |
| 乾燥減量 | ≤ 0.5% |
| 焼失残渣 | ≤ 0.1% |
| 重金属 | 10 ppm以下 |
| 融点 | 260 – 270°C (decomposes) |
| 比回転 | +120° to +130° |
| ストレージ | Store in a cool, dry place, protected from light |
| 溶解度 | Soluble in water, DMSO; slightly soluble in ethanol |
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同義語: Ergothioneine, L-Ergothioneine, Ergothioneine (EGT), (S)-α-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium inner salt, Thiohistidine betaine, 2-Mercaptohistidine trimethylbetaine, EGT, L-(+)-Ergothioneine
Ergothioneine (EGT) is a naturally occurring amino acid derivative and a potent antioxidant with unique properties. It is synthesized by certain fungi, actinomycetes, and cyanobacteria, and is accumulated in the human body through dietary sources, particularly mushrooms (especially shiitake and oyster mushrooms), black beans, and organ meats. Humans cannot synthesize ergothioneine endogenously, making it a conditionally essential nutrient.
Ergothioneine is distinguished from other antioxidants by its specific transporter, OCTN1 (SLC22A4) , which actively transports EGT into cells, enabling its accumulation at high concentrations in tissues exposed to high oxidative stress, including the liver, kidney, red blood cells, and the lens and retina of the eye. This targeted accumulation, combined with its powerful free radical scavenging activity and its ability to chelate metal ions, provides robust protection against cellular oxidative damage.
Ergothioneine is widely used in dietary supplements, functional foods, cosmetic formulations, and research applications targeting healthy aging, neurological health, skin protection, and cardiovascular support.
出典: Fermentation (using Lentinula edodes, Agaricus bisporus, or recombinant microorganisms) or synthetic production
標準化: ≥98.0% – 99.5% ergothioneine (HPLC)
フォーム: 白からオフホワイトの結晶性粉末
用途: Dietary supplements, functional foods, cosmetics, research reagents
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