| 제품명 | Nefiracetam |
| 동의어 | DM-9384; DMMPA; DZL-221; Translon; N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide; 2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)acetamide |
| CAS 번호 | 77191-36-7 |
| 분자식 | C₁₄H₁₈N₂O₂ |
| 분자량 | 246.30 g/mol |
| 외관 | 흰색에서 미백색의 결정성 분말 |
| 분석법 (HPLC) | ≥ 99.0% |
| 융점 | 125–129°C |
| 건조 손실 | ≤ 0.5% |
| 소각 잔류물 | ≤ 0.1% |
| 중금속 | 10 ppm 이하 |
| 저장 | 서늘하고 건조하며 밀폐된 곳, 빛을 피한 곳 |
도움이 필요하신가요? 저희 팀에 문의해 주세요
Nefiracetam (developmental code DM-9384) is a lipid-soluble nootropic compound belonging to the racetam family.
It is structurally distinct from other racetams due to the presence of a 2,6-dimethylphenyl group attached to the acetamide moiety.
This structural modification confers unique pharmacological properties, including GABAergic modulation (distinguishing it from most other racetams) and neuroprotective effects.
미분자: Unlike most racetams that act primarily through glutamatergic (AMPA) modulation, Nefiracetam has demonstrated significant GABAergic activity, particularly at GABA-A receptors. This unique dual mechanism (GABAergic + glutamatergic) makes Nefiracetam particularly interesting for research into anxiety, neuroprotection, and cognitive disorders with an anxiety component.
키워드:Nefiracetam CAS 77191-36-7, DM-9384, DMMPA, Translon, GABA-A modulator, dual-mechanism nootropic, neuroprotection research, racetam family, calcium channel inhibitor, LyvBio Nefiracetam
Racetam Family Comparison:
| 복합체 | 용해도 | Primary Mechanism | Unique Property |
|---|---|---|---|
| 피라세탐 | Water | AMPA (weak) | Parent compound |
| 옥시라세탐 | Water | AMPA | Learning acquisition |
| 아니라세탐 | Lipid | AMPA + nAChR | Anxiolytic |
| Nefiracetam | Lipid | AMPA + GABA-A | GABAergic modulation |
| 프라미라세탐 | Lipid | AMPA | Potent memory enhancement |
Important regulatory note: Nefiracetam is not FDA-approved for medical use in the United States. It has been investigated in clinical trials (including for Alzheimer’s disease and stroke recovery) but was not approved. It is available as a 연구용 화학물질 for laboratory use only. LyvBio supplies Nefiracetam strictly for research and development purposes.
Nefiracetam is a hydrophobic derivative of piracetam, which is generally considered to be a substance responsible for the discovery of calcium channels in the body and the indirect transfer of excitatory signaling substances as a partial agonist of calcium ion channels. Glycine binding site of NDMA receptor.
Through its effect on the cerebral cortex, nefiracetam can enhance cognitive abilities and prevent learning and memory impairment.
It does not possess muscarinic receptor agonist or antagonist properties, nor does it inhibit acetylcholinease activity.
Therefore, its anti-amnestic and memory-enhancing effects are achieved by improving the release of acetylcholine in the cerebral cortex.
| 제품 | CAS 번호. | 카테고리 | 연구 지원서 |
|---|---|---|---|
| 피라세탐 | 7491-74-9 | 라세탐 | 기억 연구, 비교 연구 |
| 아니라세탐 | 72432-10-1 | 라세탐 | AMPA + anxiolytic research |
| 옥시라세탐 | 62613-82-5 | 라세탐 | Learning acquisition research |
| 프라미라세탐 | 68497-62-1 | 라세탐 | Potent memory enhancement |
| 페닐피라세탐 | 77472-70-9 | 라세탐 | 각성제 및 인지 기능 연구 |
| 누페프트 (GVS-111) | 157115-85-0 | 이펩타이드 | Neuroprotection + cognition |
LyvBio 주식회사. is a GMP-certified supplier of high-purity Nefiracetam for research and development applications.
공급 역량:
분석법 (HPLC): ≥99.0%
양식: 결정성 분말
월간 처리량: 10kg 이상
대량 주문: 5g – 10kg
소요 기간: 3~5일 (시료), 10~15일 (대량)
문서: COA, MSDS, TDS, HPLC 크로마토그램, 안정성 데이터
품질 보증:
UV 검출을 이용한 HPLC 순도 분석
잔류 용매 검사 결과 (USP 기준 충족)
중금속 분석 (ICP-MS)
구조 확인 (요청 시 NMR 분석)
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