| Nom du produit | Néfiracétam |
| Synonymes | DM-9384; DMMPA; DZL-221; Translon; N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide; 2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)acetamide |
| Numéro CAS | 77191-36-7 |
| Formule moléculaire | C₁₄H₁₈N₂O₂ |
| Poids moléculaire | 246.30 g/mol |
| Apparence | Poudre cristalline blanche à blanc cassé |
| Essai (HPLC) | ≥ 99,01 TP3T |
| Point de fusion | 125–129°C |
| Perte au séchage | ≤ 0,5% |
| Résidu au feu | ≤ 0,11 TP3T |
| Métaux lourds | ≤ 10 ppm |
| Stockage | Dans un endroit frais, sec, hermétique et à l'abri de la lumière |
Besoin d'aide ? Contacter notre équipe
Nefiracetam (developmental code DM-9384) is a lipid-soluble nootropic compound belonging to the racetam family.
It is structurally distinct from other racetams due to the presence of a 2,6-dimethylphenyl group attached to the acetamide moiety.
This structural modification confers unique pharmacological properties, including GABAergic modulation (distinguishing it from most other racetams) and neuroprotective effects.
élément différentiateur : Unlike most racetams that act primarily through glutamatergic (AMPA) modulation, Nefiracetam has demonstrated significant GABAergic activity, particularly at GABA-A receptors. This unique dual mechanism (GABAergic + glutamatergic) makes Nefiracetam particularly interesting for research into anxiety, neuroprotection, and cognitive disorders with an anxiety component.
Mots-clés :Nefiracetam CAS 77191-36-7, DM-9384, DMMPA, Translon, GABA-A modulator, dual-mechanism nootropic, neuroprotection research, racetam family, calcium channel inhibitor, LyvBio Nefiracetam
Racetam Family Comparison:
| Complexe | Solubilité | Primary Mechanism | Unique Property |
|---|---|---|---|
| Piracétam | Water | AMPA (weak) | Composé d'origine |
| Oxiracetam | Water | AMPA | Learning acquisition |
| Aniracétam | Lipid | AMPA + nAChR | Anxiolytic |
| Néfiracétam | Lipid | AMPA + GABA-A | GABAergic modulation |
| Pramiracetam | Lipid | AMPA | Potent memory enhancement |
Important regulatory note: Nefiracetam is non approuvé par la FDA for medical use in the United States. It has been investigated in clinical trials (including for Alzheimer’s disease and stroke recovery) but was not approved. It is available as a produit chimique de recherche for laboratory use only. LyvBio supplies Nefiracetam strictly for à des fins de recherche et de développement.
Nefiracetam is a hydrophobic derivative of piracetam, which is generally considered to be a substance responsible for the discovery of calcium channels in the body and the indirect transfer of excitatory signaling substances as a partial agonist of calcium ion channels. Glycine binding site of NDMA receptor.
Through its effect on the cerebral cortex, nefiracetam can enhance cognitive abilities and prevent learning and memory impairment.
It does not possess muscarinic receptor agonist or antagonist properties, nor does it inhibit acetylcholinease activity.
Therefore, its anti-amnestic and memory-enhancing effects are achieved by improving the release of acetylcholine in the cerebral cortex.
| Produit | No CAS. | Catégorie | Demande de recherche |
|---|---|---|---|
| Piracétam | 7491-74-9 | Racétam | Recherche sur la mémoire, études comparatives |
| Aniracétam | 72432-10-1 | Racétam | AMPA + anxiolytic research |
| Oxiracetam | 62613-82-5 | Racétam | Learning acquisition research |
| Pramiracetam | 68497-62-1 | Racétam | Potent memory enhancement |
| phénylpiracétam | 77472-70-9 | Racétam | Recherche sur les stimulants et les fonctions cognitives |
| Noopept (GVS-111) | 157115-85-0 | Dipeptide | Neuroprotection + cognition |
LyvBio Co. is a GMP-certified supplier of high-purity Nefiracetam for research and development applications.
Capacités d'approvisionnement :
Dosage (HPLC) : ≥99,01 TP3T
Forme : Poudre cristalline
Capacité mensuelle : 10 kg et plus
Quantités en vrac : 5g – 10kg
Délai d'exécution : 3-5 jours (échantillons), 10-15 jours (vrac)
Documentation : Certificat d'analyse (COA), fiche de données de sécurité (FDS), fiche technique (TDS), chromatogramme HPLC, données de stabilité
L'assurance qualité :
Pureté déterminée par HPLC avec détection UV
Solvants résiduels testés (conforme à la norme USP )
Métaux lourds analysés (ICP-MS)
Confirmation de la structure (RMN sur demande)
📧 Courriel : info@lyvbio.com
🌐 Site web : https://www.lyvbio.com
English English 
Russian
French
Korean
German
Polish
Japanese
Spanish
Italian
Vietnamese