Nuciferina

Sinónimos: Nuciferine, (-)-Nuciferine, (R)-Nuciferine, Nuciferin, 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline, Aporphine alkaloid, Lotus alkaloid

C19H21NO2

Nuciferine is a naturally occurring aporphine alkaloid found in the leaves of Nelumbo nucifera (sacred lotus) and in other plants such as Nymphaea species. It is one of the primary bioactive alkaloids responsible for the pharmacological effects of lotus leaf, which has been used in Traditional Chinese Medicine (TCM) for centuries as a weight management and digestive aid.

Nuciferine has attracted significant scientific interest for its diverse biological activities, particularly its role in regulating lipid metabolism and energy balance. Its mechanism of action involves modulation of dopamine receptors, serotonin receptors, and AMPK activation, contributing to reduced appetite, increased energy expenditure, and improved glucose and lipid homeostasis.

In addition to its metabolic effects, nuciferine exhibits antioxidant, anti‑inflammatory, and neuroprotective properties. It is widely used in research studies and is increasingly incorporated into dietary supplements targeting weight management and metabolic health.

Función

• Control del peso: Modulates appetite and lipid metabolism via dopamine and serotonin receptor interactions.

• Lipid regulation: Reduces fat accumulation and supports healthy cholesterol levels.

• Activación de la AMPK: Enhances energy expenditure and glucose metabolism.

• Actividad antioxidante: Elimina los radicales libres y reduce el estrés oxidativo.

• Actividad antiinflamatoria: Modula las vías inflamatorias y la producción de citocinas.

• Efectos neuroprotectores: Favorece la función cognitiva y la salud neuronal.

Origen y pureza

• Fuente: Leaves of Nelumbo nucifera (sacred lotus) or other plants

• Normalización: ≥98.0% nuciferine (HPLC)

• Formularios: Polvo cristalino de color blanco a blanquecino

• Aplicaciones: Research studies, dietary supplements, weight management formulations

Especificaciones