Nuciferin

Synonyme: Nuciferine, (-)-Nuciferine, (R)-Nuciferine, Nuciferin, 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline, Aporphine alkaloid, Lotus alkaloid

C19H21NO2

Nuciferine is a naturally occurring aporphine alkaloid found in the leaves of Nelumbo nucifera (sacred lotus) and in other plants such as Nymphaea species. It is one of the primary bioactive alkaloids responsible for the pharmacological effects of lotus leaf, which has been used in Traditional Chinese Medicine (TCM) for centuries as a weight management and digestive aid.

Nuciferine has attracted significant scientific interest for its diverse biological activities, particularly its role in regulating lipid metabolism and energy balance. Its mechanism of action involves modulation of dopamine receptors, serotonin receptors, and AMPK activation, contributing to reduced appetite, increased energy expenditure, and improved glucose and lipid homeostasis.

In addition to its metabolic effects, nuciferine exhibits antioxidant, anti‑inflammatory, and neuroprotective properties. It is widely used in research studies and is increasingly incorporated into dietary supplements targeting weight management and metabolic health.

Funktion

• Weight management: Modulates appetite and lipid metabolism via dopamine and serotonin receptor interactions.

• Lipid regulation: Reduces fat accumulation and supports healthy cholesterol levels.

• AMPK activation: Enhances energy expenditure and glucose metabolism.

• Antioxidative Wirkung: Scavenges free radicals, reduces oxidative stress.

• Anti‑inflammatory activity: Modulates inflammatory pathways and cytokine production.

• Neuroprotektive Wirkungen: Unterstützt die kognitiven Funktionen und die Gesundheit der Nervenzellen.

Herkunft & Reinheit

• Quelle: Leaves of Nelumbo nucifera (sacred lotus) or other plants

• Standardisierung: ≥98.0% nuciferine (HPLC)

• Formulare: Weißes bis cremefarbenes kristallines Pulver

• Anwendungen: Research studies, dietary supplements, weight management formulations

Technische Daten