Nuciferina

Nuciferina

Nome del prodotto Nuciferina
Numero CAS 475-83-2
Formula molecolare C₁₉H₂₁NO₂
Peso molecolare 295.38 g/mol
Aspetto Polvere cristallina di colore da bianco a bianco sporco
Analisi (HPLC) ≥ 98,01 TP3T
Perdita per essiccazione ≤ 0,51 TP3T
Residuo di combustione ≤ 0,11 TP3T
Metalli pesanti ≤ 10 ppm
Punto di fusione 165 – 167°C
Rotazione specifica +122.0° to +128.0°
Archiviazione Store in a cool, dry place, protected from light
Solubilità Soluble in DMSO, ethanol, chloroform; slightly soluble in water
Dimensione delle particelle Da 100% a 80 mesh

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Sinonimi: Nuciferine, (-)-Nuciferine, (R)-Nuciferine, Nuciferin, 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline, Aporphine alkaloid, Lotus alkaloid

C19H21NO2

C19H21NO2

Nuciferine is a naturally occurring aporphine alkaloid found in the leaves of Nelumbo nucifera (sacred lotus) and in other plants such as Nymphaea species. It is one of the primary bioactive alkaloids responsible for the pharmacological effects of lotus leaf, which has been used in Traditional Chinese Medicine (TCM) for centuries as a weight management and digestive aid.

Nuciferine has attracted significant scientific interest for its diverse biological activities, particularly its role in regulating lipid metabolism and energy balance. Its mechanism of action involves modulation of dopamine receptors, serotonin receptors, and AMPK activation, contributing to reduced appetite, increased energy expenditure, and improved glucose and lipid homeostasis.

In addition to its metabolic effects, nuciferine exhibits antioxidant, anti‑inflammatory, and neuroprotective properties. It is widely used in research studies and is increasingly incorporated into dietary supplements targeting weight management and metabolic health.

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Funzione

  • Controllo del peso: Modulates appetite and lipid metabolism via dopamine and serotonin receptor interactions.

  • Lipid regulation: Reduces fat accumulation and supports healthy cholesterol levels.

  • AMPK activation: Enhances energy expenditure and glucose metabolism.

  • Attività antiossidante: Scavenges free radicals, reduces oxidative stress.

  • Anti‑inflammatory activity: Modulates inflammatory pathways and cytokine production.

  • Neuroprotective effects: Supports cognitive function and neuronal health.

Origine e purezza

  • Fonte: Leaves of Nelumbo nucifera (sacred lotus) or other plants

  • Standardizzazione: ≥98.0% nuciferine (HPLC)

  • Moduli: Polvere cristallina di colore da bianco a biancastro

  • Applicazioni: Research studies, dietary supplements, weight management formulations

Caratteristiche tecniche

Parametro Specifiche
Nuciferine Content (HPLC) ≥ 98,01 TP3T
Identificazione IR / MS / NMR sono conformi al riferimento
Rotazione specifica +122.0° to +128.0°
Punto di fusione 165 – 167°C
Perdita per essiccazione ≤ 0,51 TP3T
Residuo di combustione ≤ 0,11 TP3T
Metalli pesanti (espressi come Pb) ≤ 10 ppm
Arsenico (As) ≤ 1 ppm
Limiti microbiologici Conforme agli standard USP/EP

Documentazione e forniture

  • Capacità mensile: 10+ kg

  • Tempi di consegna: 3–5 giorni (campioni), 10–15 giorni (carichi)

  • Documentazione: COA, MSDS, TDS, HPLC chromatogram, stability data, NMR (upon request)

  • Imballaggio: 50g, 100g,1 kg, 2kg, 5 kg

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