ヌシフェリン

同義語： Nuciferine, (-)-Nuciferine, (R)-Nuciferine, Nuciferin, 1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline, Aporphine alkaloid, Lotus alkaloid

C19H21NO2

Nuciferine is a naturally occurring aporphine alkaloid found in the leaves of Nelumbo nucifera (sacred lotus) and in other plants such as Nymphaea species. It is one of the primary bioactive alkaloids responsible for the pharmacological effects of lotus leaf, which has been used in Traditional Chinese Medicine (TCM) for centuries as a weight management and digestive aid.

Nuciferine has attracted significant scientific interest for its diverse biological activities, particularly its role in regulating lipid metabolism and energy balance. Its mechanism of action involves modulation of dopamine receptors, serotonin receptors, and AMPK activation, contributing to reduced appetite, increased energy expenditure, and improved glucose and lipid homeostasis.

In addition to its metabolic effects, nuciferine exhibits antioxidant, anti‑inflammatory, and neuroprotective properties. It is widely used in research studies and is increasingly incorporated into dietary supplements targeting weight management and metabolic health.

機能

• 体重管理: Modulates appetite and lipid metabolism via dopamine and serotonin receptor interactions.

• Lipid regulation: Reduces fat accumulation and supports healthy cholesterol levels.

• AMPK activation: Enhances energy expenditure and glucose metabolism.

• 抗酸化活性: 活性酸素を除去し、酸化ストレスを軽減します。.

• Anti‑inflammatory activity: Modulates inflammatory pathways and cytokine production.

• Neuroprotective effects: Supports cognitive function and neuronal health.

原産地と純度

• 出典: Leaves of Nelumbo nucifera (sacred lotus) or other plants

• 標準化: ≥98.0% nuciferine (HPLC)

• フォーム: 白からオフホワイトの結晶性粉末

• 用途: Research studies, dietary supplements, weight management formulations

仕様