Sodium Taurocholate Hydrate
| Tên sản phẩm | Sodium Taurocholate Hydrate |
|---|---|
| Số CAS | 345909-26-4 |
| Công thức phân tử | C26H44NNaO7S · xH2O |
| Trọng lượng phân tử | 537.68 g/mol (anhydrous basis) |
| Hình thức | Bột tinh thể màu trắng đến trắng ngà |
| Phương pháp phân tích (HPLC) | ≥98,01 TP3T |
| Độ hòa tan | Soluble in water and ethanol; practically insoluble in non-polar solvents |
| Mất mát khi sấy khô | ≤8.0% (hydrate form) |
| Lưu trữ | Store in a cool, dry place, protected from light |
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Từ đồng nghĩa: Taurocholic acid sodium salt hydrate, Sodium taurocholate, Taurocholic acid sodium salt, Sodium cholate tautaurate, Cholyltaurine sodium salt, Sodium 2-[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]aminoethanesulfonate
Sodium Taurocholate Hydrate is the sodium salt of taurocholic acid, a primary bile acid conjugated with taurine, existing as a crystalline hydrate. It is a high-purity bile salt widely used as a biochemical surfactant and solubilizing agent in pharmaceutical and life science research. The product is typically manufactured through chemical synthesis or semi-synthesis from cholic acid, followed by conjugation with taurine and subsequent salt formation, yielding a stable hydrate form.
In the pharmaceutical and biotech industries, Sodium Taurocholate Hydrate serves as a critical excipient for enhancing the solubility and bioavailability of poorly water-soluble drugs, particularly in oral and injectable formulations. It is also a key component in cell culture media, where it facilitates lipid digestion and absorption, and finds use in membrane protein research as a mild detergent for solubilization and reconstitution. Its ability to form mixed micelles makes it indispensable in studies of bile acid metabolism, cholestasis, and drug transport mechanisms.
| Tham số | Thông số kỹ thuật |
|---|---|
| Phương pháp phân tích (HPLC) | ≥98,01 TP3T |
| Hình thức | Bột tinh thể màu trắng đến trắng ngà |
| Độ hòa tan | Soluble in water and ethanol |
| Mất mát khi sấy khô | ≤8.0% |
| Kim loại nặng | ≤10 ppm |
| Lưu trữ | Cool, dry, protected from light |
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