Sodium Taurocholate Hydrate

Sodium Taurocholate Hydrate

Название продукта Sodium Taurocholate Hydrate
Номер CAS 345909-26-4
Молекулярная формула C26H44NNaO7S · xH2O
Молекулярная масса 537.68 g/mol (anhydrous basis)
Внешний вид Кристаллический порошок от белого до небелого цвета
Анализ (ВЭЖХ) ≥98.0%
Растворимость Soluble in water and ethanol; practically insoluble in non-polar solvents
Потери при сушке ≤8.0% (hydrate form)
Хранение Store in a cool, dry place, protected from light

Sodium Taurocholate Hydrate Structure

Синонимы: Taurocholic acid sodium salt hydrate, Sodium taurocholate, Taurocholic acid sodium salt, Sodium cholate tautaurate, Cholyltaurine sodium salt, Sodium 2-[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]aminoethanesulfonate

Sodium Taurocholate Hydrate is the sodium salt of taurocholic acid, a primary bile acid conjugated with taurine, existing as a crystalline hydrate. It is a high-purity bile salt widely used as a biochemical surfactant and solubilizing agent in pharmaceutical and life science research. The product is typically manufactured through chemical synthesis or semi-synthesis from cholic acid, followed by conjugation with taurine and subsequent salt formation, yielding a stable hydrate form.

In the pharmaceutical and biotech industries, Sodium Taurocholate Hydrate serves as a critical excipient for enhancing the solubility and bioavailability of poorly water-soluble drugs, particularly in oral and injectable formulations. It is also a key component in cell culture media, where it facilitates lipid digestion and absorption, and finds use in membrane protein research as a mild detergent for solubilization and reconstitution. Its ability to form mixed micelles makes it indispensable in studies of bile acid metabolism, cholestasis, and drug transport mechanisms.

Основные особенности продукта

  • Высокая степень чистоты: ≥98% assay (HPLC) ensures consistent performance in sensitive applications.
  • Reliable Supply: Manufactured under cGMP conditions with scalable production capacity to meet bulk demands.
  • Regulatory Support: Available with comprehensive documentation including COA, MSDS, and TDS for regulatory submissions.
  • Versatile Applications: Suitable for pharmaceutical formulation, cell culture, and biochemical research.
  • Custom Packaging: Offered in various pack sizes from grams to kilograms, with custom packaging options.
  • Technical Expertise: Backed by a team of experienced chemists providing application-specific support.

Приложения

  • Solubilizing agent for lipophilic drugs in oral and parenteral formulations.
  • Component in cell culture media to enhance lipid uptake and support cell growth.
  • Detergent for membrane protein extraction and stabilization in structural biology.
  • Reference standard for analytical method development in bile acid research.
  • Excipient in drug delivery systems targeting enhanced bioavailability.

Технические характеристики

Параметр Технические характеристики
Анализ (ВЭЖХ) ≥98.0%
Внешний вид Кристаллический порошок от белого до небелого цвета
Растворимость Soluble in water and ethanol
Потери при сушке ≤8.0%
Тяжелые металлы ≤10 ppm
Хранение Cool, dry, protected from light

Заказы и поставки

  • Packaging: 1 kg, 5 kg, 25 kg fiber drums with inner polyethylene bags; custom packaging available.
  • MOQ: 1 kg (flexible for research quantities).
  • Срок выполнения заказа: 3–5 рабочих дней (товары, имеющиеся в наличии)
  • Documentation: COA, MSDS, TDS provided with each shipment.

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