Pterostilbene 4′-O-β-D-glucoside

Pterostilbene 4′-O-β-D-glucoside

Tên sản phẩm Pterostilbene 4′-O-β-D-glucoside
Số CAS 38967-99-6
Synonyms Pterostilbene glucoside; 4′-O-β-D-Glucosylpterostilbene; Pterostilbene 4′-glucoside
Công thức phân tử C22H26O8
Trọng lượng phân tử 418.44 g/mol
Hình thức Bột tinh thể màu trắng đến trắng ngà
Phương pháp phân tích (HPLC) ≥98,01 TP3T
Độ hòa tan Soluble in DMSO, methanol, ethanol; slightly soluble in water
Lưu trữ Store at 2-8°C, protected from light and moisture

Pterostilbene 4′-O-β-D-glucoside Structure

Từ đồng nghĩa: Pterostilbene glucoside, 4′-O-β-D-Glucosylpterostilbene, Pterostilbene 4′-glucoside, Pterostilbene 4′-O-beta-D-glucopyranoside

Pterostilbene 4′-O-β-D-glucoside is a naturally occurring stilbenoid glycoside found in several plant sources, including the heartwood of Pterocarpus marsupium and certain Vaccinium species. It represents the 4′-O-β-D-glucopyranoside conjugate of pterostilbene, a dimethylated analogue of resveratrol. In traditional medicine, extracts containing this compound have been used for their anti-inflammatory and antioxidant properties, particularly in Ayurvedic preparations from Pterocarpus marsupium for managing metabolic disorders.

Structurally, pterostilbene 4′-O-β-D-glucoside combines the lipophilic pterostilbene aglycone with a hydrophilic glucose moiety, which significantly alters its physicochemical behavior compared to the aglycone. This glycosylation enhances water solubility and may influence bioavailability and metabolic pathways. The compound is of interest in research for its potential role as a prodrug or active metabolite of pterostilbene, offering a different pharmacokinetic profile.

As a research-grade material, it is typically standardized to ≥98% purity by HPLC, ensuring consistent quality for in vitro and in vivo studies. It is used in investigations related to cancer chemoprevention, neuroprotection, and metabolic regulation, where the glycoside may provide advantages in delivery or stability.

Chức năng

  • Antioxidant activity: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
  • Anti-inflammatory effects: Inhibits COX-2 and downregulates pro-inflammatory cytokines.
  • Neuroprotective potential: May protect against oxidative stress-induced neuronal damage.
  • Metabolic modulation: Investigated for improving insulin sensitivity and lipid profiles.
  • Chemopreventive properties: Shows antiproliferative activity in various cancer cell lines.

Nguồn gốc và tiêu chuẩn hóa

  • Nguồn: Synthetic or isolated from Pterocarpus marsupium
  • Extraction: Enzymatic hydrolysis or chemical synthesis followed by purification
  • Tiêu chuẩn hóa: ≥98.0% (HPLC)
  • Forms: White to off-white crystalline powder
  • Ứng dụng: Research on cancer, inflammation, neuroprotection, and metabolic diseases

Thông số kỹ thuật

Tham số Thông số kỹ thuật
Phương pháp phân tích (HPLC) ≥98,01 TP3T
Xác định NMR, MS conforms to structure
Mất mát khi sấy khô ≤2.0%
Hàm lượng tro sau khi đốt ≤0.1%
Kim loại nặng ≤10 ppm
Giới hạn vi sinh vật Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g

Documentation & Supply

  • Công suất hàng tháng: 10-20 kg
  • Thời gian thực hiện: 3-5 business days (stock items)
  • Tài liệu hướng dẫn: COA, MSDS, TDS sẽ được cung cấp theo yêu cầu
  • Bao bì: 10 mg, 50 mg, 100 mg in amber glass vials; bulk orders in aluminum foil bags

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