Pterostilbene 4′-O-β-D-glucoside

Pterostilbene 4′-O-β-D-glucoside

Nom du produit Pterostilbene 4′-O-β-D-glucoside
Numéro CAS 38967-99-6
Synonymes Pterostilbene glucoside; 4′-O-β-D-Glucosylpterostilbene; Pterostilbene 4′-glucoside
Formule moléculaire C22H26O8
Poids moléculaire 418.44 g/mol
Apparence Poudre cristalline blanche à blanc cassé
Essai (HPLC) ≥98,01 TP3T
Solubilité Soluble in DMSO, methanol, ethanol; slightly soluble in water
Stockage Store at 2-8°C, protected from light and moisture

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Pterostilbene 4′-O-β-D-glucoside Structure

Synonymes : Pterostilbene glucoside, 4′-O-β-D-Glucosylpterostilbene, Pterostilbene 4′-glucoside, Pterostilbene 4′-O-beta-D-glucopyranoside

Pterostilbene 4′-O-β-D-glucoside is a naturally occurring stilbenoid glycoside found in several plant sources, including the heartwood of Pterocarpus marsupium and certain Vaccinium species. It represents the 4′-O-β-D-glucopyranoside conjugate of pterostilbene, a dimethylated analogue of resveratrol. In traditional medicine, extracts containing this compound have been used for their anti-inflammatory and antioxidant properties, particularly in Ayurvedic preparations from Pterocarpus marsupium for managing metabolic disorders.

Structurally, pterostilbene 4′-O-β-D-glucoside combines the lipophilic pterostilbene aglycone with a hydrophilic glucose moiety, which significantly alters its physicochemical behavior compared to the aglycone. This glycosylation enhances water solubility and may influence bioavailability and metabolic pathways. The compound is of interest in research for its potential role as a prodrug or active metabolite of pterostilbene, offering a different pharmacokinetic profile.

As a research-grade material, it is typically standardized to ≥98% purity by HPLC, ensuring consistent quality for in vitro and in vivo studies. It is used in investigations related to cancer chemoprevention, neuroprotection, and metabolic regulation, where the glycoside may provide advantages in delivery or stability.

Fonction

  • Activité antioxydante: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
  • Effets anti-inflammatoires: Inhibits COX-2 and downregulates pro-inflammatory cytokines.
  • Neuroprotective potential: May protect against oxidative stress-induced neuronal damage.
  • Metabolic modulation: Investigated for improving insulin sensitivity and lipid profiles.
  • Chemopreventive properties: Shows antiproliferative activity in various cancer cell lines.

Source et normalisation

  • Source: Synthetic or isolated from Pterocarpus marsupium
  • Extraction: Enzymatic hydrolysis or chemical synthesis followed by purification
  • Normalisation: ≥98.0% (HPLC)
  • Formulaires: White to off-white crystalline powder
  • Applications: Research on cancer, inflammation, neuroprotection, and metabolic diseases

Caractéristiques techniques

Paramètre Spécifications
Essai (HPLC) ≥98,01 TP3T
Identification NMR, MS conforms to structure
Perte au séchage ≤2.0%
Résidu au feu ≤ 0,11 TP3T
Métaux lourds ≤ 10 ppm
Limites microbiologiques Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g

Documentation et approvisionnement

  • Capacité mensuelle: 10-20 kg
  • Délai de livraison: 3 à 5 jours ouvrés (articles en stock)
  • Documentation: Certificat d'analyse (COA), fiche de données de sécurité (FDS) et fiche technique (TDS) disponibles sur demande
  • Emballage: 10 mg, 50 mg, 100 mg in amber glass vials; bulk orders in aluminum foil bags

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