Pterostilbene 4′-O-β-D-glucoside

Pterostilbene 4′-O-β-D-glucoside

Nazwa produktu Pterostilbene 4′-O-β-D-glucoside
Numer CAS 38967-99-6
Synonyms Pterostilbene glucoside; 4′-O-β-D-Glucosylpterostilbene; Pterostilbene 4′-glucoside
Wzór cząsteczkowy C22H26O8
Masa cząsteczkowa 418.44 g/mol
Wygląd Biały lub prawie biały krystaliczny proszek
Oznaczenie (HPLC) ≥98,01 TP3T
Rozpuszczalność Soluble in DMSO, methanol, ethanol; slightly soluble in water
Przechowywanie Store at 2-8°C, protected from light and moisture

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Pterostilbene 4′-O-β-D-glucoside Structure

Synonimy: Pterostilbene glucoside, 4′-O-β-D-Glucosylpterostilbene, Pterostilbene 4′-glucoside, Pterostilbene 4′-O-beta-D-glucopyranoside

Pterostilbene 4′-O-β-D-glucoside is a naturally occurring stilbenoid glycoside found in several plant sources, including the heartwood of Pterocarpus marsupium and certain Vaccinium species. It represents the 4′-O-β-D-glucopyranoside conjugate of pterostilbene, a dimethylated analogue of resveratrol. In traditional medicine, extracts containing this compound have been used for their anti-inflammatory and antioxidant properties, particularly in Ayurvedic preparations from Pterocarpus marsupium for managing metabolic disorders.

Structurally, pterostilbene 4′-O-β-D-glucoside combines the lipophilic pterostilbene aglycone with a hydrophilic glucose moiety, which significantly alters its physicochemical behavior compared to the aglycone. This glycosylation enhances water solubility and may influence bioavailability and metabolic pathways. The compound is of interest in research for its potential role as a prodrug or active metabolite of pterostilbene, offering a different pharmacokinetic profile.

As a research-grade material, it is typically standardized to ≥98% purity by HPLC, ensuring consistent quality for in vitro and in vivo studies. It is used in investigations related to cancer chemoprevention, neuroprotection, and metabolic regulation, where the glycoside may provide advantages in delivery or stability.

Funkcja

  • Antioxidant activity: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
  • Anti-inflammatory effects: Inhibits COX-2 and downregulates pro-inflammatory cytokines.
  • Neuroprotective potential: May protect against oxidative stress-induced neuronal damage.
  • Metabolic modulation: Investigated for improving insulin sensitivity and lipid profiles.
  • Chemopreventive properties: Shows antiproliferative activity in various cancer cell lines.

Source & Standardization

  • Źródło: Synthetic or isolated from Pterocarpus marsupium
  • Extraction: Enzymatic hydrolysis or chemical synthesis followed by purification
  • Standardization: ≥98.0% (HPLC)
  • Forms: White to off-white crystalline powder
  • Zastosowania: Research on cancer, inflammation, neuroprotection, and metabolic diseases

Dane techniczne

Parametr Specyfikacja
Oznaczenie (HPLC) ≥98,01 TP3T
Identyfikacja NMR, MS conforms to structure
Strata przy suszeniu ≤2.0%
Popiół po spaleniu ≤0,11 TP3T
Metale ciężkie ≤10 ppm
Wartości graniczne dla mikroorganizmów Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g

Documentation & Supply

  • Miesięczna wydajność: 10-20 kg
  • Czas realizacji: 3–5 dni roboczych (towary dostępne w magazynie)
  • Dokumentacja: COA, MSDS, TDS available upon request
  • Opakowanie: 10 mg, 50 mg, 100 mg in amber glass vials; bulk orders in aluminum foil bags

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