Pterostilbene 4′-O-β-D-glucoside

Pterostilbene 4′-O-β-D-glucoside

製品名 Pterostilbene 4′-O-β-D-glucoside
CAS番号 38967-99-6
同義語 Pterostilbene glucoside; 4′-O-β-D-Glucosylpterostilbene; Pterostilbene 4′-glucoside
分子式 C22H26O8
分子量 418.44 g/mol
外観 白色からオフホワイトの結晶性粉末
分析(HPLC) ≥98.0%
溶解度 Soluble in DMSO, methanol, ethanol; slightly soluble in water
ストレージ Store at 2-8°C, protected from light and moisture

Pterostilbene 4′-O-β-D-glucoside Structure

同義語: Pterostilbene glucoside, 4′-O-β-D-Glucosylpterostilbene, Pterostilbene 4′-glucoside, Pterostilbene 4′-O-beta-D-glucopyranoside

Pterostilbene 4′-O-β-D-glucoside is a naturally occurring stilbenoid glycoside found in several plant sources, including the heartwood of Pterocarpus marsupium and certain Vaccinium species. It represents the 4′-O-β-D-glucopyranoside conjugate of pterostilbene, a dimethylated analogue of resveratrol. In traditional medicine, extracts containing this compound have been used for their anti-inflammatory and antioxidant properties, particularly in Ayurvedic preparations from Pterocarpus marsupium for managing metabolic disorders.

Structurally, pterostilbene 4′-O-β-D-glucoside combines the lipophilic pterostilbene aglycone with a hydrophilic glucose moiety, which significantly alters its physicochemical behavior compared to the aglycone. This glycosylation enhances water solubility and may influence bioavailability and metabolic pathways. The compound is of interest in research for its potential role as a prodrug or active metabolite of pterostilbene, offering a different pharmacokinetic profile.

As a research-grade material, it is typically standardized to ≥98% purity by HPLC, ensuring consistent quality for in vitro and in vivo studies. It is used in investigations related to cancer chemoprevention, neuroprotection, and metabolic regulation, where the glycoside may provide advantages in delivery or stability.

機能

  • Antioxidant activity: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
  • Anti-inflammatory effects: Inhibits COX-2 and downregulates pro-inflammatory cytokines.
  • Neuroprotective potential: May protect against oxidative stress-induced neuronal damage.
  • Metabolic modulation: Investigated for improving insulin sensitivity and lipid profiles.
  • Chemopreventive properties: Shows antiproliferative activity in various cancer cell lines.

Source & Standardization

  • 出典: Synthetic or isolated from Pterocarpus marsupium
  • Extraction: Enzymatic hydrolysis or chemical synthesis followed by purification
  • Standardization: ≥98.0% (HPLC)
  • Forms: White to off-white crystalline powder
  • 用途: Research on cancer, inflammation, neuroprotection, and metabolic diseases

仕様

パラメータ 仕様
分析(HPLC) ≥98.0%
識別 NMR, MS conforms to structure
乾燥減量 ≤2.0%
焼失残渣 ≤0.11 TP3T
重金属 10 ppm以下
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g

資料・供給

  • 月間処理能力: 10-20 kg
  • リードタイム: 3~5営業日(在庫品)
  • ドキュメント: COA, MSDS, TDS available upon request
  • パッケージ: 10 mg, 50 mg, 100 mg in amber glass vials; bulk orders in aluminum foil bags

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