Magnesium L-Threonate

Magnesium L-Threonate

Magnesium L-Threonate

CAS No: 778571-57-6
Botanical source: Vitamin C, calcium carbonate, magnesium carbonate
Test Method: HPLC
Specifications: 98%
Molecular Formula: C8H14MgO10
Molecular Weight: 294.5
INCI Name: Magnesium L-Threonate
Applications: health supplement，Sports Nutrition
Synonym: Magnesium Bis[(2R,3S)-2,3,4-trihydroxybutanoate]，L-Threonate Magnesium;magnesium L-Theorate;-2,3,4-trihydroxybutanoate L-Threonic acid magnesium salt
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Magnesium L-Threonate Bulk Supplier for Cognitive & Sleep Supplements

What is Magnesium L-Threonate?

Magnesium L-Threonate is a patented magnesium compound created by combining magnesium with L-threonic acid, a vitamin C metabolite. Unlike traditional magnesium forms (oxide, citrate, glycinate), Magnesium L-Threonate was specifically designed to solve a fundamental problem: elevating brain magnesium levels effectively.
Why this matters: Most magnesium forms increase total body magnesium but fail to significantly raise cerebrospinal fluid (CSF) magnesium levels. Magnesium L-Threonate uniquely crosses the blood-brain barrier (BBB) via the SLC12A2 (NKCC1) transporter, achieving brain magnesium concentrations that other forms cannot.
Key differentiator: Magnesium L-Threonate is the only magnesium form clinically demonstrated to elevate brain magnesium levels in humans.

Magnesium L-Threonate

Applications & Market Segments

1. Cognitive Health & Memory Support (Primary Market)

Ứng dụng Liều lượng thông thường Clinical Evidence
Age-related cognitive decline 1,000–2,000 mg/day Improved executive function, working memory
Mild cognitive impairment (MCI) 1,500–2,000 mg/day Slowed progression (preliminary)
Brain fog / mental clarity 1,000–1,500 mg/day Reduced subjective cognitive complaints
Learning & neuroplasticity 1,000–2,000 mg/day Enhanced learning capacity (animal models)

2. Sleep Quality Support (Fastest Growing Segment)

Ứng dụng Dosage Cơ chế
Sleep onset (falling asleep) 1,000–2,000 mg (evening) GABA-A potentiation
Sleep maintenance (staying asleep) 1,000–2,000 mg (evening) Reduced nighttime awakenings
Age-related sleep decline 1,500–2,000 mg (evening) Restores age-depleted brain magnesium

3. Stress & Mood Support

Ứng dụng Dosage Evidence Base
General anxiety (mild-moderate) 1,000–2,000 mg/day NMDA modulation; HPA regulation
High-stress professionals 1,000–1,500 mg/day Reduced perceived stress scale (PSS)
Post-exercise recovery (mental) 1,000–2,000 mg/day Reduced mental fatigue

4. Neuroprotection (Emerging Segment)

Ứng dụng Dosage Research Status
Traumatic brain injury (TBI) recovery Research stage (animal models) Preclinical only
Neurodegenerative disease support Research stage Preclinical only

Note: Neuroprotection claims are supported primarily by animal studies. Position as “brain health support” for regulatory compliance.

Specifications

Tham số Thông số kỹ thuật Phương pháp thử nghiệm
Assay (HPLC) 98.0–101.0% HPLC
Magnesium Content 7.0–7.5% Titration / ICP-OES
L-Threonic Acid Content 65–70% HPLC
Hình thức White to off-white powder Visual
Mất mát khi sấy khô ≤ 1.0% USP <731>
Heavy Metals Pb ≤ 0.5 ppm; As ≤ 0.5 ppm; Cd ≤ 0.2 ppm ICP-MS
Residual Solvents Meet USP <467> GC
Particle Size 95% through 80 mesh Sieve Analysis

Available Product Forms & Packaging

Form Purity Ứng dụng MOQ
Standard powder ≥98% Powder，Capsules, 1–25 kg
Micronized ≥98% Gummies, stick packs 50kg

Standard packaging:

  • 1 kg aluminum foil bag (sample/trial)

  • 5 kg double PE bag + foil bag

  • 25 kg fiber drum (bulk industrial)

Shelf life: 24 months from date of manufacture in original sealed container, stored in cool, dry conditions (<25°C, <60% RH), protected from moisture and light.

Magnesium L-Threonate vs. Other Magnesium Forms

Tham số L-Threonate Glycinate Citrate Oxide
Brain magnesium elevation ✅ Yes (unique) ❌ No ❌ No ❌ No
Blood-brain barrier penetration High Very Low Very Low None
GI tolerance Excellent Excellent Moderate (osmotic) Poor
Elemental Mg % ~7% ~15% ~16% ~60%
Water solubility Good Poor Moderate None
Premium positioning Premium Mid-tier Economy Economy
Price (relative) High (1x) Low-Mid (0.3–0.4x) Low (0.2–0.3x) Very Low (0.1–0.2x)

Commercial implication: You are not selling magnesium. You are selling brain magnesium. This is how premium pricing is justified.

Câu hỏi thường gặp

Q: What makes Magnesium L-Threonate different from other magnesium forms?
>>A: It is the only magnesium form clinically demonstrated to elevate brain magnesium levels by crossing the blood-brain barrier via the SLC12A2 transporter.

Q: What is the recommended dosage for finished products?
A: General cognitive support: 1,000–1,500 mg/day. Sleep support: 1,000–2,000 mg (evening). Therapeutic applications: up to 2,000 mg/day.

Q: Is it suitable for gummy formulations?
A: Yes, but requires micronized grade to avoid grittiness and ensure homogeneous distribution.

Hỏi: Số lượng đặt hàng tối thiểu (MOQ) của quý công ty là bao nhiêu?
A: Đơn hàng mẫu: 100g–1kg. Sản xuất thử nghiệm: 5–25 kg. Sản xuất thương mại: Thỏa thuận. Thời gian giao hàng: 3–5 ngày (đơn hàng mẫu); 10–15 ngày (đơn hàng số lượng lớn).

Liên hệ với Công ty TNHH LyvBio.

📧 Email: info@lyvbio.com
🌐 Trang web: https://www.lyvbio.com

Technical inquiries receive response within 24 hours (COA, MSDS, pricing).

We supply high-quality Magnesium L-Threonate powder for:

– Bulk dietary supplement manufacturing
– Nootropic and cognitive health formulas
– Sleep and relaxation products
– Functional food and beverage applications
Available in bulk quantities from 1kg to 500kg+ with full documentation (COA, MSDS, TDS).
Thẻ:
778571-57-6 LyvBio Magnesium L-Threonate magnesium L-Theorate Magnesium L-Threonate powder supplier sleep supplement magnesium

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