YDL223C

Synonyms: YDL-223C, YDL 223C

YDL223C is a synthetic small-molecule compound that has drawn interest in medicinal chemistry and early-stage drug discovery, particularly as a tool for probing protein–protein interactions and cellular signaling pathways. While its exact target profile remains under investigation, the compound’s trifluoromethyl-substituted aryl scaffold and imidazolidinedione core place it within a well-explored chemical space known for metabolic stability and membrane permeability. Researchers frequently employ YDL223C as a reference standard or screening hit in assay development, where reproducible purity and consistent solid-state form are critical.

From a structural standpoint, YDL223C features a 4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile motif—a combination that balances lipophilic and polar character. The nitrile group offers a handle for further derivatization, while the gem-dimethyl imidazolidinedione contributes to conformational rigidity. This architecture is reminiscent of non-steroidal ligands designed to engage hydrophobic pockets, making the compound a useful probe in receptor-binding studies and structure–activity relationship (SAR) campaigns.

In the broader context of chemical biology, YDL223C is typically supplied as a high-purity solid (≥98% by HPLC) to support in vitro and cell-based experiments. Its solubility in DMSO and ethanol allows straightforward preparation of stock solutions, and the compound is stable under recommended storage conditions. While not yet a commercial therapeutic, it represents a valuable research tool for teams exploring novel mechanisms in oncology, inflammation, or metabolic disease.

Функция

• Research tool: Used as a chemical probe in target validation and pathway elucidation studies.
• Binding studies: Serves as a ligand in receptor-binding assays and protein–protein interaction screens.
• SAR campaigns: Acts as a scaffold for medicinal chemistry optimization and analog synthesis.
• Assay development: Functions as a reference standard for analytical method validation.
• Cell-based experiments: Applied in cellular assays to investigate phenotypic effects.

Source & Standardization

• Source: Synthetic chemical synthesis
• Purification: Recrystallization or chromatography to achieve high purity
• Standardization: ≥98.0% by HPLC
• Forms: White to off-white crystalline powder
• Приложения: Medicinal chemistry research, biochemical assays, drug discovery

Технические характеристики

Documentation & Supply

• Monthly capacity: 5–10 kg
• Срок выполнения заказа: 3–5 рабочих дней (товары, имеющиеся в наличии)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: Amber glass vials or sealed aluminum foil bags, desiccated

Запрос Цитировать

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