YDL223C

YDL223C

Product Name YDL223C
CAS Number 489408-02-8
Synonyms YDL-223C; YDL 223C
Appearance White to off-white crystalline powder
Purity (HPLC) ≥98.0%
Molecular Formula C17H19F3N2O2
Molecular Weight 340.34 g/mol
Solubility Soluble in DMSO, ethanol; slightly soluble in water
Storage Store at -20°C, protected from light and moisture
Package 10 mg, 50 mg, 100 mg, 500 mg, 1 g (bulk available)

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YDL223C Structure

Synonyms: YDL-223C, YDL 223C

YDL223C is a synthetic small-molecule compound that has drawn interest in medicinal chemistry and early-stage drug discovery, particularly as a tool for probing protein–protein interactions and cellular signaling pathways. While its exact target profile remains under investigation, the compound’s trifluoromethyl-substituted aryl scaffold and imidazolidinedione core place it within a well-explored chemical space known for metabolic stability and membrane permeability. Researchers frequently employ YDL223C as a reference standard or screening hit in assay development, where reproducible purity and consistent solid-state form are critical.

From a structural standpoint, YDL223C features a 4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile motif—a combination that balances lipophilic and polar character. The nitrile group offers a handle for further derivatization, while the gem-dimethyl imidazolidinedione contributes to conformational rigidity. This architecture is reminiscent of non-steroidal ligands designed to engage hydrophobic pockets, making the compound a useful probe in receptor-binding studies and structure–activity relationship (SAR) campaigns.

In the broader context of chemical biology, YDL223C is typically supplied as a high-purity solid (≥98% by HPLC) to support in vitro and cell-based experiments. Its solubility in DMSO and ethanol allows straightforward preparation of stock solutions, and the compound is stable under recommended storage conditions. While not yet a commercial therapeutic, it represents a valuable research tool for teams exploring novel mechanisms in oncology, inflammation, or metabolic disease.

Function

  • Research tool: Used as a chemical probe in target validation and pathway elucidation studies.
  • Binding studies: Serves as a ligand in receptor-binding assays and protein–protein interaction screens.
  • SAR campaigns: Acts as a scaffold for medicinal chemistry optimization and analog synthesis.
  • Assay development: Functions as a reference standard for analytical method validation.
  • Cell-based experiments: Applied in cellular assays to investigate phenotypic effects.

Source & Standardization

  • Source: Synthetic chemical synthesis
  • Purification: Recrystallization or chromatography to achieve high purity
  • Standardization: ≥98.0% by HPLC
  • Forms: White to off-white crystalline powder
  • Applications: Medicinal chemistry research, biochemical assays, drug discovery

Specifications

Parameter Specification
Assay (HPLC) ≥98.0%
Identification NMR, MS conform to structure
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g

Documentation & Supply

  • Monthly capacity: 5–10 kg
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request
  • Packaging: Amber glass vials or sealed aluminum foil bags, desiccated

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