Thiocolchicoside

Thiocolchicoside (CAS 602-41-5) is a semi-synthetic sulfur-containing derivative of the naturally occurring colchicoside, isolated from the dried seeds of Colchicum autumnale. It acts as a competitive GABAA receptor antagonist and glycine receptor agonist, providing centrally acting muscle relaxant properties. This product is supplied as a pale yellow to yellow crystalline powder with ≥98% purity (HPLC), suitable for pharmaceutical formulation development and clinical use.

As a key active pharmaceutical ingredient (API) in the treatment of acute musculoskeletal disorders, thiocolchicoside is widely incorporated into oral tablets, capsules, and topical gels. Our material meets strict pharmacopoeial standards and is accompanied by comprehensive documentation to support regulatory submissions and quality control.

Синонимы: Colchicumoside, Glaxo brand name: Muscol, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide 2-(4-methyl-1,3-thiazol-5-yl)ethyl hydrogen sulfate

Приложения

• Muscle relaxant formulations for acute low back pain and muscle spasms
• Adjuvant therapy in orthopedic and rheumatologic conditions
• Topical preparations for localized pain relief
• Research and development of central nervous system agents

Качество и документация

Every batch is tested for assay (HPLC ≥98%), loss on drying (≤1.0%), and heavy metals (≤10 ppm). Full COA, MSDS, and TDS are provided with each shipment. Stability data and impurity profiles are available upon request for qualification and registration purposes.

Упаковка и поставки

Standard packaging options include 1 kg, 5 kg, and 25 kg containers, with custom packing available on request. In-stock items ship within 3-5 business days; MOQ is 1 kg. For pricing, samples, and bulk orders, contact our sales team.

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