Pterostilbene 4′-O-β-D-glucoside

Синонимы: Pterostilbene glucoside, 4′-O-β-D-Glucosylpterostilbene, Pterostilbene 4′-glucoside, Pterostilbene 4′-O-beta-D-glucopyranoside

Pterostilbene 4′-O-β-D-glucoside is a naturally occurring stilbenoid glycoside found in several plant sources, including the heartwood of Pterocarpus marsupium and certain Vaccinium species. It represents the 4′-O-β-D-glucopyranoside conjugate of pterostilbene, a dimethylated analogue of resveratrol. In traditional medicine, extracts containing this compound have been used for their anti-inflammatory and antioxidant properties, particularly in Ayurvedic preparations from Pterocarpus marsupium for managing metabolic disorders.

Structurally, pterostilbene 4′-O-β-D-glucoside combines the lipophilic pterostilbene aglycone with a hydrophilic glucose moiety, which significantly alters its physicochemical behavior compared to the aglycone. This glycosylation enhances water solubility and may influence bioavailability and metabolic pathways. The compound is of interest in research for its potential role as a prodrug or active metabolite of pterostilbene, offering a different pharmacokinetic profile.

As a research-grade material, it is typically standardized to ≥98% purity by HPLC, ensuring consistent quality for in vitro and in vivo studies. It is used in investigations related to cancer chemoprevention, neuroprotection, and metabolic regulation, where the glycoside may provide advantages in delivery or stability.

Функция

• Antioxidant activity: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
• Anti-inflammatory effects: Inhibits COX-2 and downregulates pro-inflammatory cytokines.
• Neuroprotective potential: May protect against oxidative stress-induced neuronal damage.
• Metabolic modulation: Investigated for improving insulin sensitivity and lipid profiles.
• Chemopreventive properties: Shows antiproliferative activity in various cancer cell lines.

Source & Standardization

• Source: Synthetic or isolated from Pterocarpus marsupium
• Extraction: Enzymatic hydrolysis or chemical synthesis followed by purification
• Standardization: ≥98.0% (HPLC)
• Forms: White to off-white crystalline powder
• Приложения: Research on cancer, inflammation, neuroprotection, and metabolic diseases

Технические характеристики

Documentation & Supply

• Monthly capacity: 10-20 kg
• Срок выполнения заказа: 3–5 рабочих дней (товары, имеющиеся в наличии)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: 10 mg, 50 mg, 100 mg in amber glass vials; bulk orders in aluminum foil bags

Запрос Цитировать

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