Doramectin

Синонимы: Doramectin, Dectomax, 25-cyclohexyl-25-de(1-methylpropyl)avermectin A1a, Cyclohexylavermectin B1, UK-67994, 117704-25-3

Doramectin is a macrocyclic lactone of the avermectin family, produced through fermentation of a genetically modified strain of Streptomyces avermitilis. It is structurally related to ivermectin but features a cyclohexyl substituent at the C-25 position, which enhances its lipophilicity and prolongs its residence time in target animals. This veterinary-grade active pharmaceutical ingredient (API) is supplied as a high-purity crystalline powder, typically ≥95% by HPLC, and is used in the manufacture of injectable and pour-on antiparasitic formulations for cattle, swine, and sheep.

As a broad-spectrum endectocide, doramectin targets a wide range of internal and external parasites, including gastrointestinal nematodes, lungworms, lice, mites, and ticks. Its mechanism of action involves potentiation of glutamate-gated chloride channels, leading to paralysis and death of susceptible parasites. The compound is well established in veterinary medicine, with a proven efficacy and safety profile that makes it a cornerstone in livestock health programs. For formulators, doramectin offers reliable stability and compatibility with common excipients used in oil-based injectables and topical solutions.

Основные особенности продукта

• High purity: ≥95% assay by HPLC, ensuring consistent potency in finished formulations.
• Regulatory support: Manufactured under cGMP conditions; API is supported by a Drug Master File (DMF) for veterinary use.
• Large-scale supply: Annual production capacity exceeding 20 metric tons, with batch sizes up to 500 kg.
• Documentation: Comprehensive regulatory package available, including COA, MSDS, and TDS.
• Custom packaging: Available in 1 kg, 5 kg, and 25 kg drums to suit pilot and commercial needs.
• Technical support: Dedicated team for formulation assistance and regulatory inquiries.

Applications & Formulation Use

• Injectable solutions: Doramectin is commonly formulated as a 1% injectable solution for subcutaneous administration in cattle and swine.
• Pour-on formulations: Used in topical solutions for control of ectoparasites in cattle.
• Oral drenches: Incorporated into oral formulations for sheep and goats.
• Combination products: Blended with other antiparasitics (e.g., praziquantel) for broader spectrum activity.

Quality Specifications (QC Tests)

Bulk Supply & Ordering

• Packaging: 25 kg fiber drum with double polyethylene liner; custom packaging available upon request.
• MOQ: 1 kg for pilot trials; 25 kg for commercial orders.
• Срок выполнения заказа: 3-5 business days for stock items.
• Documentation: COA, MSDS, TDS, and DMF (upon request).

Frequently Asked Questions

What is the minimum order quantity (MOQ) for doramectin?

Our MOQ is 1 kg for pilot trials and 25 kg for commercial orders. We can accommodate smaller quantities for research purposes; please contact our sales team.

What is the typical lead time for delivery?

For stock items, the lead time is 3-5 business days from order confirmation. We maintain ample inventory to ensure prompt shipment.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, a COA is available for each batch. Samples (typically 10-50 g) can be provided for evaluation, with shipment within 1-2 days after request.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.