Doramectin

Doramectin

Product Name Doramectin
CAS Number 117704-25-3
Appearance White to off-white crystalline powder
Specifications ≥95% (HPLC)
Molecular Formula C50H74O14
Molecular Weight 899.13 g/mol
Solubility Soluble in organic solvents (e.g., ethanol, DMSO); practically insoluble in water
Loss on Drying ≤2.0%
Heavy Metals ≤10 ppm

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Doramectin Structure

Doramectin is a macrocyclic lactone endectocide, a derivative of avermectin with a unique cyclohexyl group at the C25 position. This structural modification confers enhanced lipophilicity and a longer plasma half-life compared to ivermectin, translating into sustained efficacy against a broad spectrum of internal and external parasites. It is produced by fermentation of Streptomyces avermitilis, followed by purification to a white crystalline powder with a typical assay of ≥95% (HPLC).

Primarily used in veterinary medicine, doramectin is a key active ingredient in injectable and pour-on formulations for cattle, swine, and sheep. Its activity covers gastrointestinal roundworms, lungworms, grubs, and mange mites, making it a reliable choice for parasite control programs. We supply doramectin as a raw material for formulation, backed by full analytical documentation.

Synonyms: Doramectin, 25-cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1a, Cyclohexyl avermectin B1, DOR, 117704-25-3

Applications

  • Veterinary parenteral and topical endectocide formulations
  • Combination products for broad-spectrum parasite control
  • R&D and scale-up studies for novel delivery systems

Quality & Documentation

Each batch is tested for assay, related substances, and residual solvents. COA, MSDS, and TDS are supplied per batch, and stability data are available upon request. Our quality system ensures consistency from batch to batch.

Packaging & Supply

Standard packaging is 25 kg drums, with smaller sizes (1 kg, 5 kg) available for R&D. In-stock items ship within 3–5 working days. MOQ is 1 kg. For pricing, samples, or bulk orders, contact our sales team.

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  • Our Address: 280 Main Street, Xian, Shaanxi, China
  • LyvBio Co., Ltd. — Email: info@lyvbio.com

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