Adenosine

Синонимы: Adenine riboside, 9-β-D-Ribofuranosyladenine, Vitamin B4, Adenosine, 58-61-7

Adenosine is a purine nucleoside that has quietly become one of the most versatile actives in the formulator’s toolkit. While it has been known for decades as a building block of RNA and ATP, its commercial relevance has surged in recent years across skincare, pharmaceuticals, and sports nutrition. Formulators value it for its ability to modulate cellular energy metabolism and signaling, often describing it as a ‘workhorse’ ingredient that delivers noticeable results without stability headaches.

Chemically, adenosine consists of adenine linked to a ribose sugar via a β-N9-glycosidic bond. It occurs naturally in all living cells and is produced industrially through fermentation or enzymatic conversion of adenine and ribose. The synthetic route yields a highly pure, crystalline material that is chemically identical to the naturally occurring nucleoside.

Our Adenosine is manufactured under cGMP conditions and standardized to ≥99.0% purity by HPLC. It is available in cosmetic and pharmaceutical grades, with low heavy metals and tight control on residual solvents. The fine crystalline powder dissolves readily in water, making it easy to incorporate into aqueous formulations.

Product Overview & Composition

Adenosine is a white to off-white crystalline powder with a molecular weight of 267.24 g/mol. It is freely soluble in water, slightly soluble in ethanol, and practically insoluble in non-polar solvents. The molecule is stable under normal storage conditions and is compatible with a wide range of excipients and active ingredients.

In cosmetic applications, adenosine functions as an anti-aging and soothing agent. It is known to activate adenosine A1 receptors in dermal fibroblasts, which can stimulate collagen synthesis and improve skin firmness. It also helps reduce redness and inflammation, making it suitable for sensitive skin formulations.

In the pharmaceutical and nutraceutical space, adenosine is used as a vasodilator, antiarrhythmic, and neuroprotective agent. It is a key component in cardiology diagnostics and is investigated for its role in pain modulation and sleep regulation. Its ability to increase intracellular ATP levels has led to its inclusion in sports nutrition products aimed at endurance and recovery.

Key Applications

• Anti-aging skincare: Adenosine is a proven ingredient for reducing wrinkles and improving skin elasticity. It is commonly found in serums, creams, and masks, often at concentrations of 0.1-0.5%.
• Hair care: It supports hair follicle health and can be incorporated into shampoos and conditioners to promote thicker-looking hair.
• Pharmaceutical formulations: Used in injectables for cardiac stress testing and as an antiarrhythmic agent. Also explored for neuropathic pain and epilepsy.
• Sports nutrition: Added to pre-workout and recovery supplements to boost ATP production and reduce fatigue.
• Cell culture media: A vital component in bioprocessing and research, supporting cell growth and metabolism.
• Cosmeceutical actives: Combined with other anti-aging ingredients like niacinamide and peptides for synergistic effects.

Quality & Standards

Packaging & Supply

• Packaging: 25 kg fiber drum with double polyethylene bags, or as per customer request.
• MOQ: 1 kg for sample orders; 25 kg for bulk.
• Срок выполнения заказа: 3–5 рабочих дней (товары, имеющиеся в наличии)
• Documentation: COA, MSDS, TDS, and other regulatory documents available upon request.

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• LyvBio Co., Ltd. — Электронная почта: info@lyvbio.com