Adenosine

Adenosine

Nombre del producto Adenosine
Número CAS 58-61-7
Fórmula molecular C10H13N5O4
Peso molecular 267.24 g/mol
Apariencia Polvo cristalino de color blanco a blanquecino
Ensayo (HPLC) ≥99,01 TP3T
Punto de fusión 234-236°C
Solubilidad Soluble in water (1 g/50 mL), slightly soluble in ethanol
Pérdida por secado ≤0,51 TP3T
Residuo tras la combustión ≤0,11 TP3T
Metales pesados ≤10 ppm
Paquete 25 kg fiber drum with double polyethylene bags

Adenosine Structure

Sinónimos: Adenine riboside, 9-β-D-Ribofuranosyladenine, Vitamin B4, Adenosine, 58-61-7

Adenosine is a purine nucleoside that has quietly become one of the most versatile actives in the formulator’s toolkit. While it has been known for decades as a building block of RNA and ATP, its commercial relevance has surged in recent years across skincare, pharmaceuticals, and sports nutrition. Formulators value it for its ability to modulate cellular energy metabolism and signaling, often describing it as a ‘workhorse’ ingredient that delivers noticeable results without stability headaches.

Chemically, adenosine consists of adenine linked to a ribose sugar via a β-N9-glycosidic bond. It occurs naturally in all living cells and is produced industrially through fermentation or enzymatic conversion of adenine and ribose. The synthetic route yields a highly pure, crystalline material that is chemically identical to the naturally occurring nucleoside.

Our Adenosine is manufactured under cGMP conditions and standardized to ≥99.0% purity by HPLC. It is available in cosmetic and pharmaceutical grades, with low heavy metals and tight control on residual solvents. The fine crystalline powder dissolves readily in water, making it easy to incorporate into aqueous formulations.

Descripción general y composición del producto

Adenosine is a white to off-white crystalline powder with a molecular weight of 267.24 g/mol. It is freely soluble in water, slightly soluble in ethanol, and practically insoluble in non-polar solvents. The molecule is stable under normal storage conditions and is compatible with a wide range of excipients and active ingredients.

In cosmetic applications, adenosine functions as an anti-aging and soothing agent. It is known to activate adenosine A1 receptors in dermal fibroblasts, which can stimulate collagen synthesis and improve skin firmness. It also helps reduce redness and inflammation, making it suitable for sensitive skin formulations.

In the pharmaceutical and nutraceutical space, adenosine is used as a vasodilator, antiarrhythmic, and neuroprotective agent. It is a key component in cardiology diagnostics and is investigated for its role in pain modulation and sleep regulation. Its ability to increase intracellular ATP levels has led to its inclusion in sports nutrition products aimed at endurance and recovery.

Aplicaciones principales

  • Anti-aging skincare: Adenosine is a proven ingredient for reducing wrinkles and improving skin elasticity. It is commonly found in serums, creams, and masks, often at concentrations of 0.1-0.5%.
  • Hair care: It supports hair follicle health and can be incorporated into shampoos and conditioners to promote thicker-looking hair.
  • Pharmaceutical formulations: Used in injectables for cardiac stress testing and as an antiarrhythmic agent. Also explored for neuropathic pain and epilepsy.
  • Nutrición deportiva: Added to pre-workout and recovery supplements to boost ATP production and reduce fatigue.
  • Cell culture media: A vital component in bioprocessing and research, supporting cell growth and metabolism.
  • Cosmeceutical actives: Combined with other anti-aging ingredients like niacinamide and peptides for synergistic effects.

Calidad y normas

Parámetro Especificaciones
Ensayo (HPLC) ≥99,01 TP3T
Apariencia Polvo cristalino de color blanco a blanquecino
Pérdida por secado ≤0,51 TP3T
Residuo tras la combustión ≤0,11 TP3T
Metales pesados ≤10 ppm
Límites microbianos Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent
Disolventes residuales Meets ICH Q3C guidelines

Embalaje y suministros

  • Embalaje: 25 kg fiber drum with double polyethylene bags, or as per customer request.
  • Cantidad mínima de pedido: 1 kg for sample orders; 25 kg for bulk.
  • Plazo de entrega: 3-5 días laborables (artículos en stock)
  • Documentación: COA, MSDS, TDS, and other regulatory documents available upon request.

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