Sitagliptin

Sitagliptin

제품명 Sitagliptin
CAS 번호 486460-32-6
분자식 C16H15F6N5O
분자량 407.31 g/mol
외관 흰색에서 미백색의 결정성 분말
분석법 (HPLC) ≥99%
건조 손실 ≤0.5%
소각 잔류물 ≤0.1%
중금속 ≤10 ppm
융점 ~203-207°C
특정 회전 [α]D20 = -10° to -12° (c=1, methanol)
사양 99%

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Sitagliptin Structure

동의어

  • Sitagliptin phosphate, MK-0431, Januvia, Ristaben, Tesavel, Xelevia, Sitagliptin base

Sitagliptin is one of the most widely prescribed DPP-4 inhibitors on the market, and for good reason: it helps type 2 diabetes patients manage blood glucose without the dramatic peaks and troughs that come with some older therapies. By selectively blocking the DPP-4 enzyme, it extends the half-life of incretin hormones like GLP-1, which in turn boosts insulin release when glucose is high and keeps glucagon secretion in check. The result is a smoother, more physiological control of post-meal blood sugar—exactly what clinicians and patients are looking for.

We supply sitagliptin as a high-purity API (≥99% by HPLC) in its base form, ideal for formulation into oral tablets or combination therapies. Every batch is manufactured under strict quality controls and shipped with a complete COA, so you know exactly what you’re getting. Whether you’re planning a small pilot run or gearing up for commercial-scale production, we can match your volume—from 1 kg to metric tons—with reliable lead times and global logistics.

함수

  • DPP-4 Inhibition: Selective and reversible inhibition of the dipeptidyl peptidase-4 enzyme, increasing active GLP-1 and GIP levels.
  • Glucose-Dependent Insulin Release: Enhances insulin secretion only when blood glucose is elevated, reducing the risk of hypoglycemia.
  • Glucagon Regulation: Suppresses glucagon secretion, further helping to lower hepatic glucose output.

원산지 및 순도

  • 순수함: ≥99% (HPLC), meeting or exceeding pharmacopoeia standards for sitagliptin API.
  • 외관: White to off-white crystalline powder, consistent with high-quality API.
  • 안정성: Stable under recommended storage conditions; shelf life confirmed by stability studies.

문서 및 공급

  • 문서: COA, MSDS, TDS
  • 리드 타임: Ready stock for samples; 7-15 days for bulk orders, depending on volume.
  • 포장: Available in double-layer polyethylene bags inside fiber drums (1-25 kg), or customized packaging per your request.

견적 요청

  • 주소: 중국 산시성 시안시 메인 스트리트 280번지
  • LyvBio 주식회사. — 이메일: info@lyvbio.com

연락 유지

견적 요청

주소

Room,5-0203, Courtyard 205, Lianhu District,Xi'an,Shaanxi,China

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