Sitagliptin

Sinónimos

• Sitagliptin phosphate, MK-0431, Januvia, Ristaben, Tesavel, Xelevia, Sitagliptin base

Sitagliptin is one of the most widely prescribed DPP-4 inhibitors on the market, and for good reason: it helps type 2 diabetes patients manage blood glucose without the dramatic peaks and troughs that come with some older therapies. By selectively blocking the DPP-4 enzyme, it extends the half-life of incretin hormones like GLP-1, which in turn boosts insulin release when glucose is high and keeps glucagon secretion in check. The result is a smoother, more physiological control of post-meal blood sugar—exactly what clinicians and patients are looking for.

We supply sitagliptin as a high-purity API (≥99% by HPLC) in its base form, ideal for formulation into oral tablets or combination therapies. Every batch is manufactured under strict quality controls and shipped with a complete COA, so you know exactly what you’re getting. Whether you’re planning a small pilot run or gearing up for commercial-scale production, we can match your volume—from 1 kg to metric tons—with reliable lead times and global logistics.

Función

• DPP-4 Inhibition: Selective and reversible inhibition of the dipeptidyl peptidase-4 enzyme, increasing active GLP-1 and GIP levels.
• Glucose-Dependent Insulin Release: Enhances insulin secretion only when blood glucose is elevated, reducing the risk of hypoglycemia.
• Glucagon Regulation: Suppresses glucagon secretion, further helping to lower hepatic glucose output.

Origen y pureza

• Pureza: ≥99% (HPLC), meeting or exceeding pharmacopoeia standards for sitagliptin API.
• Apariencia: White to off-white crystalline powder, consistent with high-quality API.
• Estabilidad: Stable under recommended storage conditions; shelf life confirmed by stability studies.

Documentación y suministros

• Documentación: Certificado de análisis (COA), Ficha de datos de seguridad (MSDS), Ficha técnica del producto (TDS)
• Plazo de entrega: Ready stock for samples; 7-15 days for bulk orders, depending on volume.
• Embalaje: Available in double-layer polyethylene bags inside fiber drums (1-25 kg), or customized packaging per your request.

Solicitud de presupuesto

• Nuestra dirección: Calle Main, 280, Xi'an, Shaanxi, China
• LyvBio S.L. — Correo electrónico: info@lyvbio.com