| 제품명 | Metformin Hydrochloride |
|---|---|
| CAS 번호 | 1115-70-4 |
| 분자식 | C₄H₁₁N₅ · HCl |
| 분자량 | 165.62 g/mol |
| 외관 | 흰색 결정성 분말 |
| 분석법 (HPLC) | ≥ 98.0% |
| 건조 손실 | ≤ 0.5% |
| 소각 잔류물 | ≤ 0.1% |
| 중금속 | 10 ppm 이하 |
| 융점 | 223 – 226°C |
| pH (1% 용액) | 5.0 – 7.0 |
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Metformin Hydrochloride is a biguanide compound and the hydrochloride salt form of metformin. It is one of the most widely prescribed oral antidiabetic agents in the world, recognized as the first‑line pharmacological treatment for type 2 diabetes mellitus. Metformin has been used clinically for over 60 years and is included on the WHO Model List of Essential Medicines.
Metformin works primarily by reducing hepatic glucose production (gluconeogenesis), increasing peripheral insulin sensitivity, and enhancing glucose uptake in muscle and adipose tissue. It also has beneficial effects on lipid metabolism and body weight, making it a preferred choice for patients with type 2 diabetes and obesity.
In addition to its antidiabetic applications, metformin is widely studied for its potential in anti‑aging, cardiovascular health, polycystic ovary syndrome (PCOS), and cancer prevention. Its safety profile, low cost, and multifactorial benefits have made it a compound of significant research interest beyond diabetes management.
Hepatic glucose reduction: Inhibits gluconeogenesis and glycogenolysis in the liver.
인슐린 민감도 개선: Enhances peripheral glucose uptake and utilization.
체중 관리: Associated with weight neutrality or modest weight loss.
Lipid profile support: Modulates triglyceride and cholesterol levels.
출처: Chemical synthesis
표준화: ≥98.0% metformin HCl (HPLC)
양식: White crystalline powder
응용 분야: Pharmaceutical APIs, dietary supplements, research reagents, anti‑aging formulations
| 매개변수 | 사양 |
|---|---|
| Metformin HCl Content (HPLC) | ≥ 98.0% |
| 식별 | IR / UV spectrum conforms to reference |
| pH (1% 용액) | 5.0 – 7.0 |
| Cyanoguanidine (impurity) | ≤ 0.003% |
| 건조 손실 | ≤ 0.5% |
| 소각 잔류물 | ≤ 0.1% |
| 중금속 (Pb 환산) | 10 ppm 이하 |
| 비소 (As) | ≤ 1 ppm |
| 미생물 허용 한도 | USP/EP 기준을 준수합니다 |
월간 처리 능력: 1,000+ kg
리드 타임: 3~5일 (시료), 10~15일 (대량)
문서: COA, MSDS
포장: 1kg, 5kg, 10kg, 25kg
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