Metformin HCl

Metformin HCl

Nombre del producto Metformin Hydrochloride
Número CAS 1115-70-4
Fórmula molecular C₄H₁₁N₅ · HCl
Peso molecular 165.62 g/mol
Apariencia Polvo cristalino blanco
Ensayo (HPLC) ≥ 98,01 TP3T
Pérdida por secado ≤ 0,51 TP3T
Residuo tras la combustión ≤ 0,11 TP3T
Metales pesados ≤ 10 ppm
Punto de fusión 223 – 226°C
pH (solución 1%) 5.0 – 7.0

Metformin Hydrochloride (≥98% Purity)

Sinónimos: Metformin HCl, Metformin Hydrochloride, 1,1-Dimethylbiguanide Hydrochloride, N,N-Dimethylimidodicarbonimidic diamide hydrochloride, Glucophage, Dimethylbiguanide hydrochloride

Metformin Hydrochloride is a biguanide compound and the hydrochloride salt form of metformin. It is one of the most widely prescribed oral antidiabetic agents in the world, recognized as the first‑line pharmacological treatment for type 2 diabetes mellitus. Metformin has been used clinically for over 60 years and is included on the WHO Model List of Essential Medicines.

Metformin works primarily by reducing hepatic glucose production (gluconeogenesis), increasing peripheral insulin sensitivity, and enhancing glucose uptake in muscle and adipose tissue. It also has beneficial effects on lipid metabolism and body weight, making it a preferred choice for patients with type 2 diabetes and obesity.

In addition to its antidiabetic applications, metformin is widely studied for its potential in anti‑aging, cardiovascular health, polycystic ovary syndrome (PCOS), and cancer prevention. Its safety profile, low cost, and multifactorial benefits have made it a compound of significant research interest beyond diabetes management.

Función

  • Hepatic glucose reduction: Inhibits gluconeogenesis and glycogenolysis in the liver.

  • Insulin sensitivity improvement: Enhances peripheral glucose uptake and utilization.

  • Control del peso: Associated with weight neutrality or modest weight loss.

  • Apoyo para el perfil lipídico: Modulates triglyceride and cholesterol levels.

Origen y pureza

  • Fuente: Chemical synthesis

  • Normalización: ≥98.0% metformin HCl (HPLC)

  • Formularios: Polvo cristalino blanco

  • Aplicaciones: Pharmaceutical APIs, dietary supplements, research reagents, anti‑aging formulations

Especificaciones

Parámetro Especificaciones
Metformin HCl Content (HPLC) ≥ 98,01 TP3T
Identificación IR / UV spectrum conforms to reference
pH (solución 1%) 5.0 – 7.0
Cyanoguanidine (impurity) ≤ 0.003%
Pérdida por secado ≤ 0,51 TP3T
Residuo tras la combustión ≤ 0,11 TP3T
Metales pesados (expresados en Pb) ≤ 10 ppm
Arsénico (As) ≤ 1 ppm
Límites microbianos Cumple con las normas USP/EP

Documentación y suministros

  • Capacidad mensual: más de 1.000 kg

  • Plazo de entrega: 3-5 días (muestras), 10-15 días (a granel)

  • Documentación: Certificado de análisis (COA), Ficha de datos de seguridad (FDS)

  • Embalaje: 1 kg, 5 kg, 10 kg, 25 kg

Solicitud de presupuesto

Nuestra dirección

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LyvBio S.L.
Correo electrónico: info@lyvbio.com

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