garlic extract 1%Allicin

garlic extract 1%Allicin

제품명 Allicin
CAS 번호 539-86-6
분자식 C₆H₁₀OS₂
분자량 162.27 g/mol
외관 Colorless to pale yellow liquid (pure) /

Off-white powder (stabilized form)

분석법 (HPLC) ≥synthesis 98.0% (pure); 1.0% – 5.0% (powder)

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Allicin (Garlic Extract)

Allicin is a sulfur-containing organosulfur compound and the primary bioactive constituent responsible for the characteristic odor and pharmacological activity of freshly crushed garlic (Allium sativum). It is not present in intact garlic cloves but is rapidly generated upon tissue disruption via the enzymatic conversion of its precursor, alliin (S-allyl-L-cysteine sulfoxide), by the enzyme alliinase. This conversion occurs within seconds of mechanical damage, yielding allicin as the principal thiosulfinate.
allicin is typically stabilized through encapsulation, complexation, or formulation as a standardized garlic powder extract,
with allicin content ranging from 1% in commercial preparations.
It remains one of the most extensively studied phytochemicals, with a well-documented role in infectious disease management, cardiovascular health, and immune function support.

Garlic Extract

  • Antimicrobial activity: Exhibits broad-spectrum activity against Gram-positive and Gram-negative bacteria, fungi, and viruses via thiol-modification mechanisms.

  • Cardiovascular support: Modulates lipid metabolism, platelet aggregation, and endothelial function.

  • Antioxidant activity: Directly scavenges reactive oxygen species (ROS) and induces endogenous antioxidant enzymes.

  • Anti-inflammatory activity: Suppresses NF-κB activation and pro-inflammatory cytokine production.

  • Chemical reactivity: Rapidly reacts with thiol groups; thermolabile and unstable in alkaline environments.

Source & Availability

Allicin is derived from garlic (Allium sativum L.) and is commercially available in the following forms:

  • Pure allicin (≥98.0%): Colorless to pale yellow oil; highly unstable; requires low-temperature storage and inert atmosphere.

  • Stabilized garlic extract powder: Standardized to 1.0% – 5.0% allicin content; enhanced stability through microencapsulation or complexation with cyclodextrins.

  • Garlic oil macerate: Diluted form for liquid formulations.

Supply

  • Monthly capacity: 100+ L (pure); 1,000+ kg (standardized powder)

  • Lead time: 3–5 days (samples), 10–15 days (bulk)

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