Metformin HCl

Metformin HCl

제품명 Metformin Hydrochloride
CAS 번호 1115-70-4
분자식 C₄H₁₁N₅ · HCl
분자량 165.62 g/mol
외관 흰색 결정성 분말
분석법 (HPLC) ≥ 98.0%
건조 손실 ≤ 0.5%
소각 잔류물 ≤ 0.1%
중금속 10 ppm 이하
융점 223 – 226°C
pH (1% 용액) 5.0 – 7.0

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Metformin Hydrochloride (≥98% Purity)

동의어: Metformin HCl, Metformin Hydrochloride, 1,1-Dimethylbiguanide Hydrochloride, N,N-Dimethylimidodicarbonimidic diamide hydrochloride, Glucophage, Dimethylbiguanide hydrochloride

Metformin Hydrochloride is a biguanide compound and the hydrochloride salt form of metformin. It is one of the most widely prescribed oral antidiabetic agents in the world, recognized as the first‑line pharmacological treatment for type 2 diabetes mellitus. Metformin has been used clinically for over 60 years and is included on the WHO Model List of Essential Medicines.

Metformin works primarily by reducing hepatic glucose production (gluconeogenesis), increasing peripheral insulin sensitivity, and enhancing glucose uptake in muscle and adipose tissue. It also has beneficial effects on lipid metabolism and body weight, making it a preferred choice for patients with type 2 diabetes and obesity.

In addition to its antidiabetic applications, metformin is widely studied for its potential in anti‑aging, cardiovascular health, polycystic ovary syndrome (PCOS), and cancer prevention. Its safety profile, low cost, and multifactorial benefits have made it a compound of significant research interest beyond diabetes management.

함수

  • Hepatic glucose reduction: Inhibits gluconeogenesis and glycogenolysis in the liver.

  • 인슐린 민감도 개선: Enhances peripheral glucose uptake and utilization.

  • 체중 관리: Associated with weight neutrality or modest weight loss.

  • Lipid profile support: Modulates triglyceride and cholesterol levels.

원산지 및 순도

  • 출처: Chemical synthesis

  • 표준화: ≥98.0% metformin HCl (HPLC)

  • 양식: White crystalline powder

  • 응용 분야: Pharmaceutical APIs, dietary supplements, research reagents, anti‑aging formulations

사양

매개변수 사양
Metformin HCl Content (HPLC) ≥ 98.0%
식별 IR / UV spectrum conforms to reference
pH (1% 용액) 5.0 – 7.0
Cyanoguanidine (impurity) ≤ 0.003%
건조 손실 ≤ 0.5%
소각 잔류물 ≤ 0.1%
중금속 (Pb 환산) 10 ppm 이하
비소 (As) ≤ 1 ppm
미생물 허용 한도 USP/EP 기준을 준수합니다

문서 및 공급

  • 월간 처리 능력: 1,000+ kg

  • 리드 타임: 3~5일 (시료), 10~15일 (대량)

  • 문서: COA, MSDS

  • 포장: 1kg, 5kg, 10kg, 25kg

견적 요청

주소

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