| 製品名 | Nefiracetam |
| 同義語 | DM-9384; DMMPA; DZL-221; Translon; N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide; 2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)acetamide |
| CAS番号 | 77191-36-7 |
| 分子式 | C₁₄H₁₈N₂O₂ |
| 分子量 | 246.30 g/mol |
| 外観 | 白色からオフホワイトの結晶性粉末 |
| 分析（HPLC） | ≥ 99.0% |
| 融点 | 125–129°C |
| 乾燥減量 | ≤ 0.5% |
| 焼失残渣 | ≤ 0.1% |
| 重金属 | 10 ppm以下 |
| ストレージ | 涼しく、乾燥した、密閉された、光を遮断した場所 |
お困りですか？ 弊社チームまでお問い合わせください
Nefiracetam (developmental code DM-9384) is a lipid-soluble nootropic compound belonging to the racetam family.
It is structurally distinct from other racetams due to the presence of a 2,6-dimethylphenyl group attached to the acetamide moiety.
This structural modification confers unique pharmacological properties, including GABAergic modulation (distinguishing it from most other racetams) and neuroprotective effects.
微分器： Unlike most racetams that act primarily through glutamatergic (AMPA) modulation, Nefiracetam has demonstrated significant GABAergic activity, particularly at GABA-A receptors. This unique dual mechanism (GABAergic + glutamatergic) makes Nefiracetam particularly interesting for research into anxiety, neuroprotection, and cognitive disorders with an anxiety component.
キーワード：Nefiracetam CAS 77191-36-7, DM-9384, DMMPA, Translon, GABA-A modulator, dual-mechanism nootropic, neuroprotection research, racetam family, calcium channel inhibitor, LyvBio Nefiracetam
Racetam Family Comparison:
| 複合 | 溶解度 | Primary Mechanism | Unique Property |
|---|---|---|---|
| ピラセタム | 水 | AMPA (weak) | Parent compound |
| オキシラセタム | 水 | AMPA | Learning acquisition |
| アニラセタム | Lipid | AMPA + nAChR | Anxiolytic |
| Nefiracetam | Lipid | AMPA + GABA-A | GABAergic modulation |
| プラミラセタム | Lipid | AMPA | Potent memory enhancement |
Important regulatory note: Nefiracetam is not FDA-approved for medical use in the United States. It has been investigated in clinical trials (including for Alzheimer’s disease and stroke recovery) but was not approved. It is available as a research chemical for laboratory use only. LyvBio supplies Nefiracetam strictly for research and development purposes.
Nefiracetam is a hydrophobic derivative of piracetam, which is generally considered to be a substance responsible for the discovery of calcium channels in the body and the indirect transfer of excitatory signaling substances as a partial agonist of calcium ion channels. Glycine binding site of NDMA receptor.
Through its effect on the cerebral cortex, nefiracetam can enhance cognitive abilities and prevent learning and memory impairment.
It does not possess muscarinic receptor agonist or antagonist properties, nor does it inhibit acetylcholinease activity.
Therefore, its anti-amnestic and memory-enhancing effects are achieved by improving the release of acetylcholine in the cerebral cortex.
| 製品 | CAS番号. | カテゴリ | 研究申請 |
|---|---|---|---|
| ピラセタム | 7491-74-9 | ラセタム | 記憶に関する研究、比較研究 |
| アニラセタム | 72432-10-1 | ラセタム | AMPA + anxiolytic research |
| オキシラセタム | 62613-82-5 | ラセタム | Learning acquisition research |
| プラミラセタム | 68497-62-1 | ラセタム | Potent memory enhancement |
| フェニルピラセタム | 77472-70-9 | ラセタム | 覚醒剤と認知機能に関する研究 |
| ヌーププト（GVS-111） | 157115-85-0 | ジペプチド | Neuroprotection + cognition |
リブバイオ株式会社. は、研究開発用途向けの高純度オキシラセタムを供給するGMP認証取得サプライヤーです。.
供給能力：
分析法（HPLC）： ≥99.0%
フォーム： 結晶性粉末
月間処理能力： 10 kg以上
大量注文： 5g – 10kg
リードタイム： 3～5日（サンプル）、10～15日（大量注文）
ドキュメント： COA、MSDS、TDS、HPLCクロマトグラム、安定性データ
品質保証：
UV検出を用いたHPLCによる純度測定
残留溶媒の試験結果（USP に適合）
検査対象の重金属（ICP-MS法）
構造確認（ご要望に応じてNMR分析）
📧 メールアドレス： info@lyvbio.com
🌐 ウェブサイト： https://www.lyvbio.com
English English 
Russian
French
Korean
German
Polish
Japanese
Spanish
Italian
Vietnamese