| Nome del prodotto | Nefiracetam |
| Sinonimi | DM-9384; DMMPA; DZL-221; Translon; N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide; 2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)acetamide |
| Numero CAS | 77191-36-7 |
| Formula molecolare | C₁₄H₁₈N₂O₂ |
| Peso molecolare | 246.30 g/mol |
| Aspetto | Polvere cristallina di colore da bianco a bianco sporco |
| Analisi (HPLC) | ≥ 99,01 TP3T |
| Punto di fusione | 125–129°C |
| Perdita per essiccazione | ≤ 0,51 TP3T |
| Residuo di combustione | ≤ 0,11 TP3T |
| Metalli pesanti | ≤ 10 ppm |
| Archiviazione | In un luogo fresco, asciutto, chiuso ermeticamente e al riparo dalla luce |
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Nefiracetam (developmental code DM-9384) is a lipid-soluble nootropic compound belonging to the racetam family.
It is structurally distinct from other racetams due to the presence of a 2,6-dimethylphenyl group attached to the acetamide moiety.
This structural modification confers unique pharmacological properties, including GABAergic modulation (distinguishing it from most other racetams) and neuroprotective effects.
differenziatore: Unlike most racetams that act primarily through glutamatergic (AMPA) modulation, Nefiracetam has demonstrated significant GABAergic activity, particularly at GABA-A receptors. This unique dual mechanism (GABAergic + glutamatergic) makes Nefiracetam particularly interesting for research into anxiety, neuroprotection, and cognitive disorders with an anxiety component.
Parole chiave:Nefiracetam CAS 77191-36-7, DM-9384, DMMPA, Translon, GABA-A modulator, dual-mechanism nootropic, neuroprotection research, racetam family, calcium channel inhibitor, LyvBio Nefiracetam
Racetam Family Comparison:
| Composto | Solubility | Primary Mechanism | Unique Property |
|---|---|---|---|
| Piracetam | Water | AMPA (weak) | Composto madre |
| Oxiracetam | Water | AMPA | Learning acquisition |
| Aniracetam | Lipid | AMPA + nAChR | Anxiolytic |
| Nefiracetam | Lipid | AMPA + GABA-A | GABAergic modulation |
| Pramiracetam | Lipid | AMPA | Potent memory enhancement |
Important regulatory note: Nefiracetam is not FDA-approved for medical use in the United States. It has been investigated in clinical trials (including for Alzheimer’s disease and stroke recovery) but was not approved. It is available as a research chemical for laboratory use only. LyvBio supplies Nefiracetam strictly for research and development purposes.
Nefiracetam is a hydrophobic derivative of piracetam, which is generally considered to be a substance responsible for the discovery of calcium channels in the body and the indirect transfer of excitatory signaling substances as a partial agonist of calcium ion channels. Glycine binding site of NDMA receptor.
Through its effect on the cerebral cortex, nefiracetam can enhance cognitive abilities and prevent learning and memory impairment.
It does not possess muscarinic receptor agonist or antagonist properties, nor does it inhibit acetylcholinease activity.
Therefore, its anti-amnestic and memory-enhancing effects are achieved by improving the release of acetylcholine in the cerebral cortex.
| Prodotto | N. CAS. | Categoria | Domanda di ricerca |
|---|---|---|---|
| Piracetam | 7491-74-9 | Racetam | Ricerca sulla memoria, studi comparativi |
| Aniracetam | 72432-10-1 | Racetam | AMPA + anxiolytic research |
| Oxiracetam | 62613-82-5 | Racetam | Learning acquisition research |
| Pramiracetam | 68497-62-1 | Racetam | Potent memory enhancement |
| Fenilpiracetam | 77472-70-9 | Racetam | Ricerca sugli stimolanti e sulle funzioni cognitive |
| Noopept (GVS-111) | 157115-85-0 | Dipeptide | Neuroprotection + cognition |
LyvBio S.r.l. è un fornitore certificato GMP di oxiracetam ad alta purezza destinato ad applicazioni di ricerca e sviluppo.
Capacità di fornitura:
Analisi (HPLC): ≥99,01 TP3T
Modulo: Polvere cristallina
Capacità mensile: 10+ kg
Quantità all'ingrosso: 5g – 10kg
Tempi di consegna: 3–5 giorni (campioni), 10–15 giorni (grandi quantità)
Documentazione: COA, scheda di sicurezza (MSDS), scheda tecnica (TDS), cromatogramma HPLC, dati di stabilità
Garanzia di qualità:
Purezza determinata mediante HPLC con rilevamento UV
Solventi residui analizzati (conforme alla norma USP )
Metalli pesanti analizzati (ICP-MS)
Structural confirmation (NMR upon request)
📧 E-mail: info@lyvbio.com
🌐 Sito web: https://www.lyvbio.com
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