Moxidectin

Synonymes : Moxidectin, CL 301423, ProHeart, Quest, Equest, Cydektin, 113507-06-5

Moxidectin has become a key molecule in the anti-parasitic toolbox, especially as resistance to older macrocyclic lactones grows. Formulators value it for its potency against a broad range of nematodes and arthropods, and its long half-life allows for extended protection with fewer doses. Demand is steady across veterinary and human health sectors, with particular interest in oral and injectable dosage forms for livestock, companion animals, and neglected tropical diseases.

Chemically, moxidectin is a semi-synthetic derivative of nemadectin, a fermentation product of Streptomyces cyaneogriseus noncyanogenus. It belongs to the milbemycin class, characterized by a 16-membered macrocyclic lactone ring but lacking the disaccharide substituent found in avermectins. This structural difference contributes to its distinct pharmacokinetic profile and high lipophilicity.

Commercial moxidectin is typically supplied as a white to off-white crystalline powder with a purity of ≥95% by HPLC. It is available in various grades suitable for veterinary formulations, human clinical trials, and research applications. Its stability and compatibility with common excipients make it a preferred choice for both immediate-release and long-acting formulations.

Présentation et composition du produit

Moxidectin is a single, chemically defined entity, not a mixture of homologs like some fermentation-derived avermectins. Its molecular formula is C37H53NO8, with a molecular weight of 639.8 g/mol. The molecule features a spiroketal ring system and a methoxime group at C23, which enhances its stability and lipophilicity compared to related compounds.

Our moxidectin is produced through a multi-step synthesis starting from nemadectin, followed by purification and crystallization. Each batch is tested for identity, purity, and residual solvents to ensure consistent quality. The final product is a fine powder that is practically insoluble in water but freely soluble in organic solvents such as ethanol and acetone.

Applications & Product Lines

• Veterinary parasiticides: Used in injectable and oral formulations for cattle, sheep, and swine to control gastrointestinal nematodes, lungworms, and ectoparasites.
• Companion animal health: Incorporated into spot-on and oral products for dogs and cats to prevent heartworm disease and treat hookworm and roundworm infections.
• Human antiparasitic research: Studied for the treatment of onchocerciasis (river blindness) and lymphatic filariasis, with potential for community-wide administration.
• Long-acting formulations: Utilized in sustained-release injectables and implants due to its long half-life and high potency.
• Agricultural applications: Evaluated for control of parasitic infections in aquaculture and other food-producing animals.

Quality Control Standards

Bulk Packaging & Supply

• Emballage: 25 kg fiber drum with inner polyethylene liner, sealed and labeled according to GMP standards.
• Quantité minimale de commande: 1 kg for standard orders; 100 g for sample evaluation.
• Délai de livraison: 3-5 business days for stock items.
• Documentation: COA, MSDS, TDS, and other regulatory documents available upon request.

Foire aux questions

What is the minimum order quantity (MOQ) for moxidectin?

Our standard MOQ is 1 kg for bulk orders. For sample evaluation, we can provide 100 g quantities. Custom packaging and larger volumes are available upon request.

How long does delivery take?

For stock items, delivery is typically 3-5 business days after order confirmation. We ship from our warehouse and can arrange expedited shipping if needed.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, a COA is provided with every shipment. Samples are available for evaluation; please contact our sales team to request a sample and the corresponding COA and MSDS.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.