Moxidectin

Moxidectin is a macrocyclic lactone endectocide belonging to the milbemycin family, produced by fermentation of Streptomyces cyanogriseus and modified semisynthetically. Its unique methoxime group at C23 and olefinic side chain at C25 confer a longer plasma half-life and broader spectrum of activity compared to avermectins. We supply moxidectin as a white to off-white powder, ≥98% purity by HPLC, suitable for veterinary pharmaceutical formulations and R&D use.

The compound acts by binding to glutamate-gated chloride channels in nematodes and arthropods, causing paralysis and death. Its high lipophilicity ensures excellent tissue distribution and persistent efficacy, making it a preferred choice for monthly heartworm preventives and treatment of parasitic infections in livestock and companion animals.

Synonyms: Moxidectin (USAN), CL 301,423, Cydectin, ProHeart, Moxidectin B1, 23-O-methyloxime milbemycin B1

Applications

• Veterinary anthelmintic formulations for cattle, sheep, and horses
• Companion animal heartworm preventives and ectoparasite control
• Research and development of endectocide analogs
• Custom dosage forms for pharmaceutical partners

Quality & Documentation

Every batch is tested for assay (HPLC ≥98%), loss on drying (≤1.0%), and heavy metals (≤10 ppm). Full COA, MSDS, and TDS are available on request; stability data can be provided for qualification.

Packaging & Supply

Standard packaging: 1 kg, 5 kg, 25 kg; bulk and custom packing available. In-stock items ship within 3-5 days; MOQ from 1 kg. For pricing, samples, and bulk orders, contact our sales team.

Request For Quote

• Our Address: 280 Main Street, Xian, Shaanxi, China
• LyvBio Co., Ltd. — Email: info@lyvbio.com