Lamotrigine

Synonyms :Lamictal, BW-430C, 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine, 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine, Lamotrigine base, Lamotrigine USP

Lamotrigine is a phenyltriazine derivative that functions as an anticonvulsant and mood-stabilizing agent. It is primarily used in the management of epilepsy and bipolar disorder, where it helps to stabilize neuronal membranes by blocking voltage-sensitive sodium channels and inhibiting the release of excitatory neurotransmitters, particularly glutamate. This mechanism of action contributes to its efficacy in reducing seizure frequency and preventing mood episodes.

As a pharmaceutical intermediate, lamotrigine is a key active pharmaceutical ingredient (API) in the production of antiepileptic and psychiatric medications. Its well-characterized profile and established therapeutic benefits make it a valuable compound for both research and commercial applications.

Fonction

• Anticonvulsant Activity: Inhibits voltage-gated sodium channels, stabilizing presynaptic neuronal membranes and reducing abnormal electrical discharges in the brain.
• Glutamate Release Inhibition: Modulates the release of excitatory amino acids, particularly glutamate, thereby dampening excitatory neurotransmission and preventing seizure propagation.
• Mood Stabilization: Exhibits efficacy in bipolar disorder by prolonging the time to depressive and manic episodes, likely through similar ion channel modulation and neurotransmitter regulation.
• Neuroprotective Effects: Demonstrates potential neuroprotective properties in models of ischemia and excitotoxicity, supporting its use in neurological conditions.

Origine et pureté

• Source: Synthetic compound produced via chemical synthesis, with high purity suitable for pharmaceutical use.
• Normalisation: Conforms to USP/EP specifications; assay (HPLC) 98.0% – 101.0% on dried basis.
• Formulaires: Available as a crystalline powder, typically in bulk quantities for formulation or further processing.
• Applications: Used as an API in tablets, oral suspensions, and other dosage forms for epilepsy and bipolar disorder; also employed in research and development.

Documentation et approvisionnement

• Documentation: certificat d'analyse (COA), fiche de données de sécurité (FDS), fiche technique (TDS)
• Délai de livraison: 7-15 days after order confirmation, depending on quantity and destination.
• Emballage: Supplied in double polyethylene bags inside fiber drums or as per customer request; net weight 25 kg per drum.

Demande de devis

• Notre adresse: 280, rue Main, Xi'an, Shaanxi, Chine
• LyvBio Co. — E-mail : info@lyvbio.com

How to Order Lamotrigine  from LyvBio? It’s simple!

Just drop us an email at info@lyvbio.com and let us know:

De combien en avez-vous besoin ?

Votre adresse de livraison ?

Nous vous répondrons dans les 24 heures pour vous communiquer les tarifs, le certificat d'analyse (COA) et les détails d'expédition. Nous prenons en charge les commandes d'échantillons et les expéditions en gros, avec la formule DDP disponible pour l'Europe.