Magnesium L-Threonate

Magnesium L-Threonate

N° CAS : 778571-57-6
Origine botanique : Vitamin C, calcium carbonate, magnesium carbonate
Méthode d'essai : HPLC
Caractéristiques techniques : 98%
Formule moléculaire : C8H14MgO10
Poids moléculaire : 294.5
Nom INCI : Magnesium L-Threonate
Applications : health supplement,Sports Nutrition
Synonyme : Magnesium Bis[(2R,3S)-2,3,4-trihydroxybutanoate],L-Threonate Magnesium;magnesium L-Theorate;-2,3,4-trihydroxybutanoate L-Threonic acid magnesium salt

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Magnesium L-Threonate Bulk Supplier for Cognitive & Sleep Supplements

What is Magnesium L-Threonate?

Magnesium L-Threonate is a patented magnesium compound created by combining magnesium with L-threonic acid, a vitamin C metabolite. Unlike traditional magnesium forms (oxide, citrate, glycinate), Magnesium L-Threonate was specifically designed to solve a fundamental problem: elevating brain magnesium levels effectively.
Why this matters: Most magnesium forms increase total body magnesium but fail to significantly raise cerebrospinal fluid (CSF) magnesium levels. Magnesium L-Threonate uniquely crosses the blood-brain barrier (BBB) via the SLC12A2 (NKCC1) transporter, achieving brain magnesium concentrations that other forms cannot.
Key differentiator: Magnesium L-Threonate is the only magnesium form clinically demonstrated to elevate brain magnesium levels in humans.
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Magnesium L-Threonate

Applications & Market Segments

1. Cognitive Health & Memory Support (Primary Market)

Application Posologie habituelle Clinical Evidence
Age-related cognitive decline 1,000–2,000 mg/day Improved executive function, working memory
Mild cognitive impairment (MCI) 1,500–2,000 mg/day Slowed progression (preliminary)
Brain fog / mental clarity 1,000–1,500 mg/day Reduced subjective cognitive complaints
Learning & neuroplasticity 1,000–2,000 mg/day Enhanced learning capacity (animal models)

2. Sleep Quality Support (Fastest Growing Segment)

Application Dosage Mécanisme
Sleep onset (falling asleep) 1,000–2,000 mg (evening) GABA-A potentiation
Sleep maintenance (staying asleep) 1,000–2,000 mg (evening) Reduced nighttime awakenings
Age-related sleep decline 1,500–2,000 mg (evening) Restores age-depleted brain magnesium

3. Stress & Mood Support

Application Dosage Evidence Base
General anxiety (mild-moderate) 1,000–2,000 mg/day NMDA modulation; HPA regulation
High-stress professionals 1,000–1,500 mg/day Reduced perceived stress scale (PSS)
Post-exercise recovery (mental) 1,000–2,000 mg/day Reduced mental fatigue

4. Neuroprotection (Emerging Segment)

Application Dosage Research Status
Traumatic brain injury (TBI) recovery Research stage (animal models) Preclinical only
Neurodegenerative disease support Research stage Preclinical only

Note: Neuroprotection claims are supported primarily by animal studies. Position as “brain health support” for regulatory compliance.

Caractéristiques techniques

Paramètre Spécifications Méthode d'essai
Essai (HPLC) 98.0–101.0% HPLC
Teneur en magnésium 7.0–7.5% Titration / ICP-OES
L-Threonic Acid Content 65–70% HPLC
Apparence Poudre blanche à blanc cassé Visuel
Perte au séchage ≤ 1,01 TP3T USP
Métaux lourds Pb ≤ 0.5 ppm; As ≤ 0.5 ppm; Cd ≤ 0.2 ppm ICP-MS
Solvants résiduels Découvrez la norme USP GC
Granulométrie 95% jusqu'au tamis de 80 mesh Analyse granulométrique

Available Product Forms & Packaging

Form Pureté Applications MOQ
Standard powder ≥98% Powder,Capsules, 1–25 kg
Micronized ≥98% Gummies, stick packs 50kg

Standard packaging:

  • 1 kg aluminum foil bag (sample/trial)

  • 5 kg double PE bag + foil bag

  • 25 kg fiber drum (bulk industrial)

Shelf life: 24 months from date of manufacture in original sealed container, stored in cool, dry conditions (<25°C, <60% RH), protected from moisture and light.

Magnesium L-Threonate vs. Other Magnesium Forms

Paramètre L-Threonate Glycinate Citrate Oxide
Brain magnesium elevation ✅ Yes (unique) ❌ No ❌ No ❌ No
Blood-brain barrier penetration Élevé Very Low Very Low None
GI tolerance Excellent Excellent Moderate (osmotic) Poor
Elemental Mg % ~7% ~15% ~16% ~60%
Water solubility Good Poor Moderate None
Premium positioning Premium Mid-tier Economy Economy
Price (relative) High (1x) Low-Mid (0.3–0.4x) Low (0.2–0.3x) Very Low (0.1–0.2x)

Commercial implication: You are not selling magnesium. You are selling brain magnesium. This is how premium pricing is justified.

Foire aux questions

Q: What makes Magnesium L-Threonate different from other magnesium forms?
>>A: It is the only magnesium form clinically demonstrated to elevate brain magnesium levels by crossing the blood-brain barrier via the SLC12A2 transporter.

Q: What is the recommended dosage for finished products?
A: General cognitive support: 1,000–1,500 mg/day. Sleep support: 1,000–2,000 mg (evening). Therapeutic applications: up to 2,000 mg/day.

Q: Is it suitable for gummy formulations?
A: Yes, but requires micronized grade to avoid grittiness and ensure homogeneous distribution.

Q : Quelle est votre quantité minimale de commande ?
A: Sample orders: 100g–1kg. Trial production: 5–25 kg. Commercial: Negotiable. Lead time: 3–5 days (samples); 10–15 days (bulk).

Contactez LyvBio Co., Ltd.

📧 Courriel : info@lyvbio.com
🌐 Site web : https://www.lyvbio.com

Technical inquiries receive response within 24 hours (COA, MSDS, pricing).

We supply high-quality Magnesium L-Threonate powder for:

– Bulk dietary supplement manufacturing
– Nootropic and cognitive health formulas
– Sleep and relaxation products
– Functional food and beverage applications
Available in bulk quantities from 1kg to 500kg+ with full documentation (COA, MSDS, TDS).

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