L-Ergothioneine

Ergothioneine (L-Ergothioneine)

Synonyms: Ergothioneine, L-Ergothioneine, Ergothioneine (EGT), (S)-α-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium inner salt, Thiohistidine betaine, 2-Mercaptohistidine trimethylbetaine, EGT, L-(+)-Ergothioneine

Ergothioneine (EGT) is a naturally occurring amino acid derivative and a potent antioxidant with unique properties. It is synthesized by certain fungi, actinomycetes, and cyanobacteria, and is accumulated in the human body through dietary sources, particularly mushrooms (especially shiitake and oyster mushrooms), black beans, and organ meats. Humans cannot synthesize ergothioneine endogenously, making it a conditionally essential nutrient.

Ergothioneine is distinguished from other antioxidants by its specific transporter, OCTN1 (SLC22A4) , which actively transports EGT into cells, enabling its accumulation at high concentrations in tissues exposed to high oxidative stress, including the liver, kidney, red blood cells, and the lens and retina of the eye. This targeted accumulation, combined with its powerful free radical scavenging activity and its ability to chelate metal ions, provides robust protection against cellular oxidative damage.

Ergothioneine is widely used in dietary supplements, functional foods, cosmetic formulations, and research applications targeting healthy aging, neurological health, skin protection, and cardiovascular support.

Product Highlights

• High Purity: Minimum 99% purity, meeting rigorous quality standards.
• Natural Source: Fermentation-derived, offering a clean and sustainable production method.
• Potent Antioxidant: Exhibits superior free radical scavenging activity, protecting cells from oxidative damage.
• Stable Compound: Chemically stable under various conditions, suitable for diverse applications.
• Comprehensive Documentation: Full COA, MSDS, and TDS available upon request.

Applications

• Dietary supplements for cellular health and antioxidant support.
• Cosmetic formulations for skin protection and anti-aging.
• Research applications in oxidative stress and neuroprotection studies.

Source & Purity

• Source: Fermentation (using Lentinula edodes, Agaricus bisporus, or recombinant microorganisms) or synthetic production

• Standardization: ≥98.0% – 99.5% ergothioneine (HPLC)

• Forms: White to off-white crystalline powder

• Applications: Dietary supplements, functional foods, cosmetics, research reagents

Ordering & Supply

• Packaging:  1kg, and custom packaging available.
• MOQ:1kg for research samples.
• Lead time: In stock for standard sizes, 5-7 days for larger quantities.
• Documentation: COA,and allergen statement provided.

Request For Quote

• Our Address:Shaanxi, China
• LyvBio Co., Ltd.
• Email: info@lyvbio.com