Palmitoyl Pentapeptide-4

Palmitoyl Pentapeptide-4

Tên sản phẩm Palmitoyl Pentapeptide-4
Số CAS 214047-00-4
Công thức phân tử C39H75N9O7
Trọng lượng phân tử 802.06 g/mol
Hình thức Bột màu trắng đến trắng ngà
Độ tinh khiết (HPLC) ≥95.0%
Độ hòa tan Soluble in water, ethanol, and propylene glycol
Lưu trữ Store at 2-8°C, protected from light and moisture
Gói 1 g, 10 g, 100 g, or 1 kg in amber glass bottles or aluminum foil bags

Palmitoyl Pentapeptide-4 Structure

Từ đồng nghĩa: Pal-GQPR, Palmitoyl-Gly-Gln-Pro-Arg, Matrixyl 3000 Component, N-Palmitoyl-Glycyl-L-Glutaminyl-L-Prolyl-L-Arginine, Palmitoyl Pentapeptide-3, Matrixyl

Palmitoyl Pentapeptide-4 is a synthetic lipopeptide that has become a staple in advanced anti-aging formulations. Its structure features a palmitic acid moiety conjugated to the N-terminus of the pentapeptide sequence glycine-glutamine-proline-arginine (GQPR), a fragment derived from the procollagen I alpha-1 chain. This lipophilic modification enhances skin penetration, allowing the peptide to reach deeper layers of the epidermis where it can exert its biological effects. Since its introduction in the early 2000s, it has been widely studied for its ability to support collagen synthesis and improve the appearance of aging skin.

The mechanism of action involves the stimulation of collagen types I, III, and IV, as well as fibronectin and hyaluronic acid production. Unlike topical retinoids that can cause irritation, Palmitoyl Pentapeptide-4 offers a gentler alternative with a favorable safety profile. It is often combined with other peptides, such as Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, to create synergistic anti-aging complexes. Its efficacy has been validated in numerous in vitro and clinical studies, demonstrating visible reductions in wrinkle depth and improved skin texture.

As a cosmetic ingredient, Palmitoyl Pentapeptide-4 is typically supplied as a high-purity powder (≥95% HPLC) that is easily incorporated into emulsions, serums, and gels. It is compatible with a broad range of formulation ingredients and is stable under normal storage conditions. The recommended usage level ranges from 1% to 5%, depending on the desired effect and the specific product format. Its versatility and proven performance make it a valuable asset for formulators targeting the premium anti-aging market.

Chức năng

  • Collagen stimulation: Upregulates collagen I, III, and IV synthesis, improving skin firmness and elasticity.
  • Wrinkle reduction: Clinically shown to reduce the depth of fine lines and wrinkles.
  • Extracellular matrix support: Promotes fibronectin and hyaluronic acid production for enhanced skin hydration.
  • Skin repair: Accelerates wound healing and improves overall skin texture.
  • Anti-aging: Delays the visible signs of aging by supporting dermal structure.

Nguồn gốc và tiêu chuẩn hóa

  • Nguồn: Synthetic peptide, produced via solid-phase peptide synthesis.
  • Độ tinh khiết: ≥95% (HPLC).
  • Form: White to off-white powder.
  • Độ hòa tan: Water-soluble, also soluble in ethanol and glycols.
  • Ứng dụng: Anti-aging creams, serums, lotions, and other cosmetic formulations.

Thông số kỹ thuật

Tham số Thông số kỹ thuật
Phương pháp phân tích (HPLC) ≥95.0%
Xác định Matches reference standard
Hình thức Bột màu trắng đến trắng ngà
Water Content ≤5,0%
Kim loại nặng ≤10 ppm
Giới hạn vi sinh vật Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent

Documentation & Supply

  • Công suất hàng tháng: 50 kg
  • Thời gian thực hiện: 3-5 business days (stock items)
  • Tài liệu hướng dẫn: COA, MSDS, TDS sẽ được cung cấp theo yêu cầu
  • Bao bì: 1 g, 10 g, 100 g, or 1 kg in amber glass bottles or aluminum foil bags

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