Netobimin
| Tham số | Thông số kỹ thuật |
|---|---|
| Tên sản phẩm | Netobimin |
| Số CAS | 60719-84-8 |
| Công thức phân tử | C17H17N3O3S |
| Trọng lượng phân tử | 343.4 g/mol |
| Hình thức | Bột tinh thể màu trắng đến trắng ngà |
| Phương pháp phân tích (HPLC) | ≥98,01 TP3T |
| Độ hòa tan | Slightly soluble in water, soluble in dimethyl sulfoxide and dimethylformamide |
| Gói | 25 kg fiber drum with double polyethylene liner |
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Từ đồng nghĩa: Netobimin, N-(3-Methoxycarbonylamino-2-nitrophenyl)methanesulfonamide, SCH 32481, Hapadex, Netobiminum
Netobimin has drawn steady attention from formulators across the veterinary and pharmaceutical sectors as a reliable, broad-spectrum anthelmintic. It is particularly valued in markets where resistance to older benzimidazoles is a growing concern, and where producers need a compound that performs consistently in both oral drenches and feed premixes. Its profile makes it a practical choice for sheep, cattle, and swine parasite control programs.
Chemically, Netobimin is a sulfonamide-substituted benzimidazole prodrug. After administration, it is metabolized in the liver to albendazole and albendazole sulfoxide, the active entities that disrupt parasite microtubule formation. This metabolic conversion gives Netobimin a distinct pharmacokinetic edge, delivering the proven efficacy of albendazole while offering favorable handling and formulation characteristics in its native form.
LyvBio supplies Netobimin at ≥98.0% purity (HPLC), manufactured under strict quality systems and available in bulk quantities for pharmaceutical and veterinary finished-dose production. Each lot is accompanied by a comprehensive Certificate of Analysis, and our technical team can support formulation inquiries with solubility and stability data.
Netobimin is a synthetic benzimidazole derivative with the molecular formula C17H17N3O3S and a molecular weight of 343.4 g/mol. It appears as a white to off-white crystalline powder, slightly soluble in water but readily soluble in polar aprotic solvents such as dimethyl sulfoxide and dimethylformamide. This solubility profile is advantageous for liquid drench formulations where uniform suspension is critical.
The compound functions as a prodrug. Once absorbed, hepatic metabolism converts it to albendazole, which then undergoes further oxidation to albendazole sulfoxide. This active metabolite binds to parasite β-tubulin, inhibiting microtubule polymerization and ultimately causing energy depletion and death of the parasite. The prodrug design also helps reduce the bitter taste often associated with albendazole, improving palatability in oral formulations.
| Test Item | Thông số kỹ thuật |
|---|---|
| Xác định | IR and HPLC retention time conform to reference standard |
| Mất mát khi sấy khô | ≤0.5% |
| Kim loại nặng | ≤20 ppm |
| Organic Impurities | ≤1.0% total, ≤0.5% individual |
| Giới hạn vi sinh vật | Total aerobic count ≤1000 CFU/g; absence of E. coli and Salmonella |
We offer a low MOQ of 1 kg for trial and R&D purposes. For commercial supply, the standard MOQ is 25 kg, though we can accommodate larger volumes with scheduled deliveries.
For stock items, delivery is 3-5 business days from order confirmation. We maintain inventory of Netobimin to ensure rapid fulfillment.
Yes, a Certificate of Analysis is provided with every shipment. Samples of 10-50 g are available upon request for quality evaluation, typically dispatched within 1-2 days.
send us your specification for a quotation.
Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China
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