Netobimin

Synonyme: Netobimin, N-(3-Methoxycarbonylamino-2-nitrophenyl)methanesulfonamide, SCH 32481, Hapadex, Netobiminum

Netobimin has drawn steady attention from formulators across the veterinary and pharmaceutical sectors as a reliable, broad-spectrum anthelmintic. It is particularly valued in markets where resistance to older benzimidazoles is a growing concern, and where producers need a compound that performs consistently in both oral drenches and feed premixes. Its profile makes it a practical choice for sheep, cattle, and swine parasite control programs.

Chemically, Netobimin is a sulfonamide-substituted benzimidazole prodrug. After administration, it is metabolized in the liver to albendazole and albendazole sulfoxide, the active entities that disrupt parasite microtubule formation. This metabolic conversion gives Netobimin a distinct pharmacokinetic edge, delivering the proven efficacy of albendazole while offering favorable handling and formulation characteristics in its native form.

LyvBio supplies Netobimin at ≥98.0% purity (HPLC), manufactured under strict quality systems and available in bulk quantities for pharmaceutical and veterinary finished-dose production. Each lot is accompanied by a comprehensive Certificate of Analysis, and our technical team can support formulation inquiries with solubility and stability data.

Produktübersicht und Zusammensetzung

Netobimin is a synthetic benzimidazole derivative with the molecular formula C17H17N3O3S and a molecular weight of 343.4 g/mol. It appears as a white to off-white crystalline powder, slightly soluble in water but readily soluble in polar aprotic solvents such as dimethyl sulfoxide and dimethylformamide. This solubility profile is advantageous for liquid drench formulations where uniform suspension is critical.

The compound functions as a prodrug. Once absorbed, hepatic metabolism converts it to albendazole, which then undergoes further oxidation to albendazole sulfoxide. This active metabolite binds to parasite β-tubulin, inhibiting microtubule polymerization and ultimately causing energy depletion and death of the parasite. The prodrug design also helps reduce the bitter taste often associated with albendazole, improving palatability in oral formulations.

Applications & Product Lines

• Veterinary oral drenches: Netobimin is widely formulated as a suspension for sheep and cattle, targeting gastrointestinal nematodes, lungworms, and tapeworms.
• Feed premixes: Its stability in premix matrices allows incorporation into medicated feed for swine and poultry, supporting herd-level parasite management.
• Combination antiparasitics: Netobimin can be co-formulated with other actives, such as triclabendazole, to broaden spectrum coverage against liver flukes and nematodes.
• Forschungs- und Referenzstandards: The high-purity material serves as a reference standard for analytical method development and pharmacokinetic studies.
• Custom formulation development: LyvBio supports clients developing novel delivery systems, including sustained-release boluses and injectable preparations.

Quality Control Standards

Bulk Packaging & Supply

• Verpackung: 25 kg fiber drums with double polyethylene liners, or as requested for smaller quantities.
• Mindestbestellmenge: 1 kg for trial orders; 25 kg for commercial scale.
• Lieferzeit: 3-5 business days for stock items.
• Dokumentation: COA, MSDS, TDS, and if required, stability data and method validation reports.

Häufig gestellte Fragen

What is the minimum order quantity?

We offer a low MOQ of 1 kg for trial and R&D purposes. For commercial supply, the standard MOQ is 25 kg, though we can accommodate larger volumes with scheduled deliveries.

How long does delivery take?

For stock items, delivery is 3-5 business days from order confirmation. We maintain inventory of Netobimin to ensure rapid fulfillment.

Can you provide a COA and samples?

Yes, a Certificate of Analysis is provided with every shipment. Samples of 10-50 g are available upon request for quality evaluation, typically dispatched within 1-2 days.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.