Pyridoxine hydrochloride

Synonyms: Vitamin B6 hydrochloride, Pyridoxol hydrochloride, 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride, Aderoxine, Hexa-Betalin, Pyridoxinium chloride

Pyridoxine hydrochloride is the synthetic hydrochloride salt of pyridoxine (vitamin B6), a water-soluble vitamin that plays an essential role in amino acid metabolism, neurotransmitter synthesis, and hemoglobin production. Unlike the other B6 vitamers—pyridoxal and pyridoxamine—pyridoxine is the most stable and commonly used form in pharmaceutical and nutritional applications. Its hydrochloride salt further enhances stability and aqueous solubility, making it the preferred choice for oral solid dosage forms, injectables, and fortified foods.

First isolated in the 1930s and chemically synthesized shortly thereafter, pyridoxine hydrochloride has become a staple in clinical nutrition and preventive medicine. It serves as a precursor to pyridoxal 5′-phosphate (PLP), the biologically active coenzyme that catalyzes over 140 enzymatic reactions, including transamination, decarboxylation, and racemization. This central role in nitrogen metabolism explains its widespread use in treating deficiencies, alleviating nausea during pregnancy, and managing certain types of anemia and neuropathy.

In the pharmaceutical industry, pyridoxine hydrochloride is formulated into tablets, capsules, and sterile solutions, often in combination with other B-complex vitamins. It is also a key ingredient in energy drinks, infant formula, and dietary supplements, where it supports normal neurological function and red blood cell formation. Its well-documented safety profile and excellent stability make it a reliable choice for formulators worldwide.

Chức năng

• Coenzyme precursor: Converts to pyridoxal 5′-phosphate (PLP), essential for amino acid and neurotransmitter metabolism.
• Neurological support: Aids in the synthesis of serotonin, dopamine, and GABA, supporting mood and nerve function.
• Hematopoietic activity: Plays a role in hemoglobin synthesis and prevention of sideroblastic anemia.
• Nausea management: Clinically used to alleviate nausea and vomiting during pregnancy, often with doxylamine.
• Chức năng miễn dịch: Supports lymphocyte proliferation and antibody production.
• Homocysteine regulation: Helps maintain normal homocysteine levels, supporting cardiovascular health.

Nguồn gốc và tiêu chuẩn hóa

• Nguồn: Synthetic chemical synthesis
• Production: Multi-step organic synthesis followed by hydrochloride salt formation and purification
• Tiêu chuẩn hóa: 98.0%–102.0% (HPLC, on dried basis)
• Forms: White crystalline powder
• Ứng dụng: Pharmaceutical tablets, capsules, injectables, dietary supplements, food fortification, animal feed

Thông số kỹ thuật

Documentation & Supply

• Công suất hàng tháng: 50 metric tons
• Thời gian thực hiện: 3-5 business days (stock items)
• Tài liệu hướng dẫn: COA, MSDS, TDS, GMP, ISO 9001, Halal, Kosher
• Bao bì: 25 kg fiber drum with double polyethylene liner, or as per customer request

Yêu cầu báo giá

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