Sodium Taurochenodeoxycholate
| Название продукта | Sodium Taurochenodeoxycholate |
|---|---|
| Номер CAS | 6009-98-9 |
| Молекулярная формула | C26H44NNaO6S |
| Молекулярная масса | 521.68 g/mol |
| Внешний вид | Кристаллический порошок от белого до небелого цвета |
| Анализ (ВЭЖХ) | ≥98.0% |
| Потери при сушке | ≤5.0% |
| Тяжелые металлы | ≤10 ppm |
| Растворимость | Soluble in water, ethanol; practically insoluble in non-polar solvents |
| Упаковка | 1 kg, 5 kg, 25 kg fiber drums with inner polyethylene bags |
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Синонимы: TCDCA sodium salt, Sodium taurochenodeoxycholate, Taurochenodeoxycholic acid sodium salt, 2-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]aminoethanesulfonic acid sodium salt, Chenodeoxycholyltaurine sodium salt
Sodium Taurochenodeoxycholate (TCDCA) is the sodium salt form of taurochenodeoxycholic acid, a primary bile acid conjugated with taurine. It occurs naturally in the bile of mammals, including humans, and plays a critical role in lipid digestion and absorption. As a commercial product, it is typically produced through chemical synthesis or semi-synthesis from chenodeoxycholic acid, ensuring high purity and consistent quality for industrial and research applications.
In the pharmaceutical and biotechnology sectors, TCDCA is valued for its ability to modulate bile acid receptors such as FXR and TGR5, making it a subject of interest in metabolic and liver-related research. It also serves as a key component in cell culture media, particularly for hepatocyte studies, and as a reference standard in analytical chemistry. Its amphiphilic nature allows it to act as a detergent, facilitating the solubilization of membrane proteins and lipids in various biochemical assays.
| Параметр | Технические характеристики |
|---|---|
| Анализ (ВЭЖХ) | ≥98.0% |
| Внешний вид | White to off-white powder |
| Идентификация | IR, NMR conforms to structure |
| Потери при сушке | ≤5.0% |
| Тяжелые металлы | ≤10 ppm |
| Остаточные растворители | Meets ICH Q3C limits |
| Microbial Limits | Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g |
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